%0 Journal Article %A Mohamed Badawy %A Salah Asieda %T Effect of low tidal volume during general anesthesia for urological procedures on lung functions %D 2015 %R 10.1183/13993003.congress-2015.PA1824 %J European Respiratory Journal %P PA1824 %V 46 %N suppl 59 %X Background: post-operative lung function impairment is common after surgery specially in the lateral decubitus position. Evidence suggests that if we use low tidal volume during mechanical ventilation this may limit post-operative lung injury. We compared post-operative lung functions in patients put in the lateral position when ventilated with low Vs. high tidal volumes .Methods: This prospective open label clinical trial was performed on 104 patients ASA I &II scheduled for elective urological operations done in the right or left lateral position expected to last more than 2 hours. Patients were divided into two groups : group L ventilated with 5-7 ml/kg tidal volume, with positive end expiratory pressure(PEEP) 5-10 cm H2O and recruitment maneuver (RM) and group H ventilated with 10-12 ml/kg tidal volume without PEEP and no recruitment maneuver. Pulmonary functions were measured pre-operatively and 6,12,24 hours after extubation.Results: Better pulmonary functions were found in the first post-operative six hours in the low tidal volume group and significant difference was found in all parameters.FVC and FEV1/FVC were significantly higher in the low tidal volume group ( P= 0.001) after 12 hours of extubation. After 24 hours there was significant difference in the predicted FEV1,& FVC, &FEV1/FVC ratio (P=0.001)being higher in the low tidal volume group.Conclusion: In comparison with conventional mechanical ventilation, a lung protective strategy using low tidal volume with 5-10 cm H2O PEEP and RM did improved lung functions in the first post-operative 24 hours. The overall postoperative follow up did not show significant difference between the two groups. %U