RT Journal Article
SR Electronic
T1 Bacteraemia in outpatient with community-acquired pneumonia
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA2583
DO 10.1183/13993003.congress-2015.PA2583
VO 46
IS suppl 59
A1 Catia Cilloniz
A1 Chiara Traverso
A1 Chiara Chiurazzi
A1 Albert Gabarrus
A1 Ernesto Rangel
A1 Francesc Marco
A1 Josep Mensa
A1 Antoni Torres
YR 2015
UL http://erj.ersjournals.com/content/46/suppl_59/PA2583.abstract
AB Background: Community-acquired pneumonia (CAP) remains a common and potentially life-threatening condition; we aimed to determine the incidence, microbial aetiology, risk factors and outcomes of bacteremic CAP that received outpatient care.Methods: Between January 2000 and July 2014 we prospectively evaluated all consecutive patients with CAP treated as outpatients; every patient had at least one blood culture.Results: We studied 372 patients treated outside the hospital, 26 (7%) presented bacteraemia, PSI clasess I- II (90%) and CURB65 0-1 (91%) of these group. Only S. pneumoniae (93%) and H. influenzae (7%) was found in bacteremic cases. A multivariate analysis showed : age ≥50 years, pleuritic pain, and C-reactive protein ≥22.9 mg/dL were independently associated with bacteraemia . None of the patients with bacteremia was readmitted or died.VariableUnivariateMultivariate*OR95% CIp-valueOR95% CIp-valueAge ≥ 50 years2.471.1-5.50.0283.161.1-8.40.021Prior antibiotic treatment0.260.06-1.10.070Pleuritic pain2.501.02-6.10.0444.061.3-11.80.010C-reactive protein ≥22.9 mg/dL8.813.4-22.70.00110.083.7-27.20.001WBC count ≥10 x 109/L2.280.8-5.80.087Significant univariate and multivariate logistic regression analyses of predictors for bacteraemia in outpatientsConclusions: following our findings we proposed a score based on age, C-reactive protein and pleuritic pain to suspect bacteremia in outpatients with CAP.