RT Journal Article
SR Electronic
T1 Retrospective analysis of viral pneumonia cases due to pandemic H3N2
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA2611
DO 10.1183/13993003.congress-2015.PA2611
VO 46
IS suppl 59
A1 Coskun Dogan
A1 Sevda Sener Comert
A1 Benan Caglayan
A1 Serap Gencer
A1 Elif Torun Parmaksiz
A1 Ali Fidan
A1 Banu Salepci
YR 2015
UL http://erj.ersjournals.com/content/46/suppl_59/PA2611.abstract
AB Aim: To evaluate clinical, laboratory, radiological and demographic data of H3N2 pneumonia cases admitted to Pulmonology department during H3N2 pandemic season and compare with non-H3N2 community acquired pneumonia (CAP) cases.Methods: The study population consisted of all CAP cases admitted to our Pulmonology department between December 2013 – February 2014 influenza season. The patient files were evaluated for physical findings, laboratory data, radiological findings, treatment and outcome of cases. H3N2 was diagnosed by polymerase chain reaction (PCR) of throat swabs. The clinical, radiological and laboratory findings of H3N2 pneumonia cases were compared with non-H3N2 pneumonia cases. Mann Whitney U, Ki-square, Fisher's exact, logistic regression analysis by forward stepwise method were used for statistical analyses. P value <0.05 was considered significant.Results: During H3N2 pandemic season, 69 cases were diagnosed as CAP; 62 (89,8%) were non-H3N2 CAP, 7(10,2%) were H3N2 pneumonia. The demographic data, CURB-65, PSI scores, clinical, radiological and laboratory findings of two gorups were similar (p>0,05). The rates of treatment failure and/or transport to intensive care unit with need of invasive mechanical ventilation were significantly higher in H3N2 group (71,4% vs. 25,8%, p=0,024; OR: 7,18; 95%CI: 1,26 – 40,77). Mortality rates were similar in both groups ((p>0.05).Conclusion: The need of MV and intensive care treatment is more frequent in H3N2 pneumonia cases. Correct diagnosis, close follow-up and intensive care support is of vital importance in patients admitted due to CAP during influenza season and suspected to have viral pneumonia.