RT Journal Article SR Electronic T1 Tuberculosis in native and foreign born populations in Portugal JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA2743 DO 10.1183/13993003.congress-2015.PA2743 VO 46 IS suppl 59 A1 Raquel Duarte A1 João Paulino A1 Ana Martins A1 Miguel Machado A1 Rita Gaio YR 2015 UL http://erj.ersjournals.com/content/46/suppl_59/PA2743.abstract AB Tuberculosis (TB) is a major global health problem. Over the last 20 years, although industrialized countries have shown changes in overall TB notifications with decreasing incidence in native population and increasing incidence in foreign-born populations.The objective was to characterize the risk factors associated with TB among native and foreign-born tuberculosis patients between 1 January 2008 and 31 December 2012 in Portugal.Retrospective case-control study was done to characterize the risk factors associated with tuberculosis among native and foreign-born population in Portugal. The medical records of all TB cases notified between the 1 january 2008 and 31 december 2012 were analysed.We analyzed 2092 foreign-born and 4294 native-born patients. 1362 (65%) of the foreign-borns were male with mean age 35.99 years (± 15.78). The native population had 2722 males (63%) with mean age 45.34 (± 20.86). HIV positivity [adjusted odds ratio (OR):2.143; 95% CI: 1.643-2.796], was the risk factor more frequently found in foreign-born cases; drug abuse was less frequently found in foreign-born cases (OR: 0.328; 95% CI: 0.229-0.470) and employment was more frequent among the foreign born group (OR: 1.458 95% CI: 1.204-1.764). The outcome of the disease and the time between the onset of symptoms and diagnosis were not statistically different between the 2 groups (p=1).The outcome and the period between symptom and diagnosis did not differ between the two studied groups. The risk factors associated with TB cases are different between the two populations. There is a need to define different strategies in these two populations.