TY - JOUR T1 - Effectiveness of a biofeedback intervention toward weaning the difficult-to-wean MV patients JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2015.OA3263 VL - 46 IS - suppl 59 SP - OA3263 AU - Ching-I. Li AU - Yu-Ju Chen AU - I-Chen Lin AU - Shing-Shan Guo Y1 - 2015/09/01 UR - http://erj.ersjournals.com/content/46/suppl_59/OA3263.abstract N2 - Background: Psychological trauma is commonly found in difficult-to-wean patients requiring prolonged mechanical ventilation (MV). It is important to develop a proper intervention to break the vicious cycle of psychological and physiological distress and promote the successful ventilator weaning.Objectives: To test the effectiveness of biofeedback intervention for MV patientsin terms of the change of their psychophysiological responses and perceived control.Methods: This was a randomized controlled trial. Forty-seven subjects were recruited from a medical center and randomized assigned into experimental and control groups, 26 and 21 subjects respectively. The experimental group received the biofeedback intervention for 4 weeks, while the control group received standard care. The repeated psychophysiological measurements were conducted in both groups.Results: The results showed that psychophysiological indicators had improved in the experimental group, which includes significant decrease in fear of intubated with mechanical ventilation (-5.5 ± 2.1, p < 0.01), fear of weaning trial (-4.9 ± 2.5, p < 0.01), dyspnea ( -4.5 ± 2.3, p < 0.01), Shortened State Anxiety Scale (-8.1 ± 3.5, p < 0.01), and rapid shallow breathing index (-32.5 ± 25.7, p < 0.01). While the perceived control (5.2 ± 2.0, p <.01) and finger temperature (2.3 ± 2.4, p < 0.05) also had significantly increased. However, heart rate variability indices did not show significantly different within or between two groups.Conclusion: Through the HRV biofeedback intervention, MV patients can decrease anxiety, fear, and dyspnea, and also increase their perceived control during mechanical ventilation and weaning process. ER -