RT Journal Article
SR Electronic
T1 Forcede expiratory volume in six second in the spirometric diagnosis of COPD
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA2274
DO 10.1183/13993003.congress-2015.PA2274
VO 46
IS suppl 59
A1 Leifu Jiang
A1 Kaisheng Yin
A1 Ping Yan
YR 2015
UL http://erj.ersjournals.com/content/46/suppl_59/PA2274.abstract
AB Objective: To evaluate the efficacy of FEV6as surrogate for FVC in the diagnosis of COPD, and to determine the fixed cut-off point of FEV1/FEV6 which can be used as an alternative for FEV1/FVCMethods Spirometry measurements were performed in 128 COPD patients, FEV1,FEV6,FVc, FEV1% pred, FVC% pred FEV1/FVC,and FEV1/FEV6 were measured and analyzed. FEV1/FVC < 70% was used as the "gold stadard".Severity of obstruction was based on FEV1% pred.Results: There were 51% participants with FEV1/FVC>=70%,49% with FEV1/FVC <70%.Linear correlation was revealed between FEV1/FVC and FEV1/FEV6 with the value close to 1.From ROC curve analysis, the FEV1/FVE6<71.14% was the best cut-off point corresponding to FEV1/FVC <70%.Conclusion: These reseach results suggest that FEV1/FEV6 is a valid alternative to FEV1/FVC for spirometric diagnosis of airway obstruction.