PT - JOURNAL ARTICLE AU - Gulbanu Horzum Ekinci AU - Osman Haciomeroglu AU - Serda Kanbur Metin AU - Ayse Ersev AU - Pinar Atagun Guney AU - Çagatay Tezel AU - Adnan Yilmaz TI - Clinicopathological characteristics and treatment outcomes of pulmonary carcinosarcoma in eight patients AID - 10.1183/13993003.congress-2015.PA4308 DP - 2015 Sep 01 TA - European Respiratory Journal PG - PA4308 VI - 46 IP - suppl 59 4099 - http://erj.ersjournals.com/content/46/suppl_59/PA4308.short 4100 - http://erj.ersjournals.com/content/46/suppl_59/PA4308.full SO - Eur Respir J2015 Sep 01; 46 AB - Background: Pulmonary carcinosarcoma is a rare malignant tumor of the lung, accounting for only 0.1 to 1 % of all pulmonary neoplasms.Aim: The aim of the present study was to evaluate clinical, radiological, and pathological findings and treatment outcomes of patients with pulmonary carcinosarcoma.Methods: We retrospectively reviewed the records of pathology department from the beginning of 2005 to the end of 2013.Results: The present study included eight cases with pulmonary carcinosarcoma. All patients were male and their ages ranged from 56 to 77 years, with mean age of 63.1 years. The most common radiological finding was a solitary mass, followed by atelectasis and mass. All patients underwent surgical resection. Operations were lobectomy (n=6), bilobectomy inferior (n=1), and pneumonectomy (n=1). Pathological diagnosis of pulmonary carcinosarcoma was made by surgical resection in all patients. Pathologically, the epithelial component of the tumor was squamous cell carcinoma in 4 patients and adenocarcinoma in 4 patients. The most common sarcomatous component was spindle cell, followed by chondrosarcoma. Four patients received adjuvant chemotherapy. Survival time for four patients was shorter than one year. The median survival time was 21.5 months (range: 1-75 months).Conclusions: pulmonary carcinosarcoma of the lung is a rare biphasic tumor. Complete surgical resection is the treatment of choice for this tumor. The prognosis of patients with pulmonary carcinosarcoma is poor despite complete surgical resection and adjuvant chemotherapy.