RT Journal Article SR Electronic T1 LATE-BREAKING ABSTRACT: Increasing physical activity in patients with COPD using a telecoaching program: A multicenter RCT JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP OA278 DO 10.1183/13993003.congress-2015.OA278 VO 46 IS suppl 59 A1 Heleen Demeyer A1 Zafeiris Louvaris A1 Rebecca Tanner A1 Noah Rubio A1 Anja Frei A1 Corina de Jong A1 Elena Gimeno Santos A1 Maarten Spruyt A1 Matthias Loeckx A1 Sara Buttery A1 Claire Yerramasu A1 Gilbert Buesching A1 Alexandra Strassmann A1 Ignasi Serra A1 Roberto Rabinovich A1 Iannis Vogiatzis A1 Michael Polkey A1 Judith Garcia Aymerich A1 Thierry Troosters YR 2015 UL http://erj.ersjournals.com/content/46/suppl_59/OA278.abstract AB Rationale: Increasing physical activity (PA) is a desired outcome in patients with COPD. We aimed to investigate the effectiveness of a 3 month tele-coaching program on the PA level of patients with COPD in a multicenter European trial (NCT02158065).Methods: In this RCT 344 patients (64% male, FEV1%pred 56(21), age 66(8)y, 6MWD 443(106)m, BMI 26(5) kg.m-2, 4890(2778)steps.day-1, 488(200)VMU.min-1) from 6 centers were allocated to a usual care group (UCG) or an intervention group (IG) receiving a tele-coaching program, including a step counter providing direct feedback, an exercise booklet, a dedicated smartphone application (Linkcare), text messages and occasional telephone contacts with investigators. A daily goal (number of steps) was sent and revised every week. PA was measured using accelerometry during 1 week preceding randomization and during week 12. Mean daily step count and vector magnitude units (VMU) were chosen as outcome.Results: Both groups were comparable at baseline, for all variables except VMU [UCG vs IG respectively 512(207) vs 465(190)VMU.min-1]. 40% of patients in the intervention group vs 12% of control patients (p<0.001) increased PA with by least 20% from baseline (OR[95%CI] for increase 4.69 [2.46-8.97] in IG vs UCG). Intervention patients had an increase of 1546 [95%CI 1021-2072] steps.day-1 (p<0.001) and an increase of 87 [95%CI 54-121] VMU.min-1 (p<0.001) more than controls. Within group changes (Δ) for IG vs UCG were respectively 934(2482) vs -673(1688) steps.day-1 and 55(148) vs -39(122)VMU.min-1.Conclusion: Physical activity can be significantly increased in patients with COPD using a step counter and a smartphone based, semi-automated tele-coaching program.