PT - JOURNAL ARTICLE AU - Irina Ponomareva AU - Vladimir Abrosimov AU - Natalia Peregudova TI - Assessment of parameters of lung ventilation during 6-minute walk test in patients with COPD AID - 10.1183/13993003.congress-2015.PA1029 DP - 2015 Sep 01 TA - European Respiratory Journal PG - PA1029 VI - 46 IP - suppl 59 4099 - http://erj.ersjournals.com/content/46/suppl_59/PA1029.short 4100 - http://erj.ersjournals.com/content/46/suppl_59/PA1029.full SO - Eur Respir J2015 Sep 01; 46 AB - Patients with COPD have reduced exercise tolerance. Low tolerance to physical exercise in patients with COPD is multifactorial and is due to several reasons, rather important of which is reduction of lung ventilation ability. Registration of indices of ventilation during the test widens diagnostic possibilities of 6-minute walk test (6 MWT).Materials and methods: male patients with COPD (n=34) II-IV degree of severity, average age 57,5±7,1, FEV146,8 ±14,3% predicted and male patients without COPD, average age 60,8±4,6, FEV193,3±14,4% predicted are involved in the investigation. This investigation was held on the equipment Spiropalm 6 MWT (Cosmed, Italy), which allows to measure parameters of minute ventilation (VE) in the process of standardized 6 MWT.Results: distance, walked by patients with COPD was 362,3 ± 10,3 m and in control group 510,4 ± 15,6 (p<0,05). Indices of initial ventilation in groups weren't significantly different VE 8,9±3,6 l / min in group of patients with COPD and 7,6±4,5 l/min (p>0,05) in control group; according to peak ventilation significant differences 17,4±8,8 l/min and VE 29,5±13,7 l/min (p<0,05) are marked; according to indices of final ventilation significant differences VE 15,4±9,5 l/min and 26,5±12,9 l/min (p<0,05) are also marked.Conclusion: studying the ventilation parameters during exercise tests in patients with COPD can be used for identification of reasons, limiting tolerance to physical exercise, what, finally, will allow to provide personified approach to programme of treatment of patients with COPD. Measuring of ventilation indices during 6 MWT widens assessment of functional status of the patient.