RT Journal Article
SR Electronic
T1 Survival in lung cancer: Associated factors in Tunisian patients
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA4310
DO 10.1183/13993003.congress-2015.PA4310
VO 46
IS suppl 59
A1 Boutheina Melki
A1 Samira Aouadi
A1 Houda Gahrsalli
A1 Dorra Bejar
A1 Soumaya Laabidi
A1 Sonia Maâlej
A1 Leila Douik el Gharbi
YR 2015
UL http://erj.ersjournals.com/content/46/suppl_59/PA4310.abstract
AB Introduction: Lung cancer remains a relevant health care problem in the world and Tunisia. Despite the advanced therapeutic, his prognosis still poor. Knowledge of prognostic factors is important for making the therapeutic decision.Objective: The aim of the study is to analyze survival in lung cancer and to investigate the association between clinical characteristics, treatment and prognosis.Methods: A retrospective study was conducted including 183 patients admitted between January 2010 and December 2011 with diagnosis of lung cancer.Results: Mean age was 61 ± 10 years. The sex ratio was 6.32 M/F. A smoking history was noted in 85% of cases. Non small cell lung cancer (NSCLC) was the most common histological type (89%). Small cell carcinoma (SCC) was identified in 11 % of cases. At diagnosis, 67% of patients were metastatic, 23% were at a locally advanced stage. Only 5% of patients had a localized tumor.Therapeutic decision was taken in a multidisciplinary team meeting in 52% of cases. Surgical treatment was possible in only 8% of cases. Palliative chemotherapy was prescribed in 66% of patients, radiotherapy in 25% of cases. Patients with SCC were treated by chemotherapy in 75% associated with radiotherapy in 56 % of cases. Supportive care was indicated in 19% of cases.The median of survival was 12 ± 1 month. Factors associated with long survival were age less than 65 years, performance status (0 or 1), absence of lung fibrosis history, absence of metastatic lymph nodes, adenocarcinoma type and multidisciplinar approach.Conclusion: survival in Tunisian patients with lung cancer is low.Screening,early diagnosis andmultidisciplinary approach may improve the prognosis of the disease.