RT Journal Article SR Electronic T1 GPs based Swiss chronic obstructive pulmonary disease (COPD) cohort: Disease management in primary care: Descriptive data JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3867 DO 10.1183/13993003.congress-2015.PA3867 VO 46 IS suppl 59 A1 Nebal Abu Hussein A1 Pascal Urwyler A1 P.O Bridevaux A1 P.N Chhajed A1 J.W. Fitting A1 Thomas Geiser A1 Ladina Joos Zellweger A1 Melcom Kohler A1 Sabrina Maier A1 David Miedinger A1 Salome Schafroth Török A1 Robert Thurnheer A1 Michael Tamm A1 Joerg Daniel Leuppi YR 2015 UL http://erj.ersjournals.com/content/46/suppl_59/PA3867.abstract AB Background: COPD is known to be a progressive disease and a major burden in health system. Our objective was to analyze the progression of the disease and disease management under primary care setting over long term period.Methods: COPD patients were screened by GPS and enrolled into our cohort. Demographic data was collected; medical treatment, spirometric parameters, exacerbation history, treatment and disease progression were recorded every six months.Results: 1160 patients with chronic bronchitis (61% male, 47% current smoker) were screened at baseline. Only 60% of patients at baseline have COPD (50% in GOLD II and GOLD III). Most of the patients have combined therapy of min. 2 medication, ; fewer than 10% of the subjects have pulmonary rehab. The longest observation period lasted over 30 month. 51% of our patients have a medium risk for exacerbation. We registered 962 exacerbation and 36 death events 15 of them were due to an exacerbation. We recorded 456 events, which went from healthy to an exacerbation, besides more than 200 incidents the second exacerbation occurs immediately after the first one.Conclusion: our data shows that COPD is often under- and misdiagnosed in primary care and often treated poorly. This is probably due to poor knowledge of guidelines.