RT Journal Article SR Electronic T1 Correlation between exposure to secondhand smoke load and hemodynamic parameters, lung function and autonomic nervous system JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA1886 DO 10.1183/13993003.congress-2015.PA1886 VO 46 IS suppl 59 A1 Juliana Souza Uzeloto A1 Dionei Ramos A1 Ana Paula Coelho Figueira Freire A1 Bruna Soplador de Alencar Silva A1 Marceli Rocha Leite A1 Renata Marques David A1 Fabiano Francisco de Lima A1 Iara Buriola Trevisan A1 Gabriel Faustino Santa BrĂ­gida A1 Giovanna Altero Arevalo A1 Guilherme Yassuyuki Tacao A1 Ercy Mara Cipulo Ramos YR 2015 UL http://erj.ersjournals.com/content/46/suppl_59/PA1886.abstract AB Introduction: It is known that the damage caused by smoking can be extended to passive smokers; however, there are still gaps from passive exposure to cigarette smoke. Objective: To verify the correlation betweenfrequency and duration of exposure of passive smoking and hemodynamic parameters, lung function and autonomic nervous system.Methods: 38 passive smokers, exposed daily to cigarette smoke, were evaluated. An initial assessment and evaluation of lung function were performed. Next, to analyze the autonomic nervous system, heart rate variability data were collected using a heart rate monitor at rest for 20 minutes. Hemodynamic parameters were measured. We questioned the frequency of exposure (exposure times daily) and the exposure time (in years).Results: There was a significant correlation (p<0.05) between the frequency of exposure and diastolic blood pressure (r=0.3526), oxygen saturation (r=-0.3624) and FEF 25-75% (r=-0.3734). In the analysis of the autonomic nervous system there was a global reduction in the autonomic activity according to the exposure time, characterized by a negative correlation in the SDNN (r=-0.4578) and SD2 (r=-0.4716) indexes and in the sympathetic activity represented by LFms2 (r=-0.4767).A reduction in vagal activity (RMSSD (r=-0.4449), HFms2(r=-0.4932) HFnu (r=-0.5078) and SD1 (r=-0.4449)), increased sympathetic activity LFnu (r=0.4231) as well as a reduction in autonomic balance LF/HF (r=0.4979) was also observed, according to the frequency of exposure.Conclusion: Passive smokers presented a correlation between passive exposure load and damage to the hemodynamic parameters, lung function and autonomic nervous system.