RT Journal Article
SR Electronic
T1 Development of lung function in infancy in 'healthy' preterm infants
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA4154
DO 10.1183/13993003.congress-2015.PA4154
VO 46
IS suppl 59
A1 De Mir, Ines
A1 Sardon, Olaia
A1 Corcuera, Paula
A1 Sanchez Solís, Manuel
A1 Caballero, Araceli
A1 Hoo, A.F.
A1 Pérez, Virginia
A1 González Perez-Yarza, Eduardo
A1 Moreno-Galdó, Antonio
YR 2015
UL https://publications.ersnet.org//content/46/suppl_59/PA4154.abstract
AB Even in the absence of overt respiratory disease during the neonatal period, reduced lung function (LF) has been reported in preterm infants. We have previously found significantly lower Crs, V'maxFRC, FEV0.5 and FEF25-75 in “healthy” preterm infants when compared to term controls (ERS de Mir, 2014)Objectives: To assess LF at 6 and 18 months of age in preterm infants without neonatal respiratory disease, and compare the measurements to those obtained in healthy fullterm infants.Methods: LF was measured under chloral sedation in 'healthy' preterm (30-35.8 w) and fullterm Spanish White babies, using the CareFusionTM Masterscreen BabyBody equipment. Results were expressed as z scores to adjust for sex, age and body size (Lum, Ped Pulm 2010; Nguyen, Ped Pulm 2013).Results: 156 infants were initially studied at mean (SD) corrected postnatal age (cPNA) of 5.9 (1.0) months. 112 (57 term and 55 preterm) were followed up at 18.3 and 18.2 months respectively. At 18 months cPNA, results were similar between the groups View this table:LFT follow up at 18 m cPNAConclusions: The differences observed in our cohort between term controls and 'healthy' preterm infants at 6 months cPNA in Crs, V'maxFRC, FEV 0,5 and FEF 25-75% was no longer evident at 18 months corrected age, suggesting a catch-up of lung function in this group of preterm infants.