TY - JOUR T1 - Pulmonary tumour thrombotic microangiopathy: unclassifiable pulmonary hypertension? JF - European Respiratory Journal JO - Eur Respir J SP - 1214 LP - 1217 DO - 10.1183/13993003.00052-2015 VL - 46 IS - 4 AU - Neelam Kumar AU - Laura C. Price AU - M. Angeles Montero AU - Konstantinos Dimopoulos AU - Athol U. Wells AU - S. John Wort Y1 - 2015/10/01 UR - http://erj.ersjournals.com/content/46/4/1214.abstract N2 - Pulmonary hypertension (PH) is defined as a mean pulmonary artery pressure ≥25 mmHg, and can be associated with multiple conditions. The diagnostic strategy and treatment of PH is heavily reliant on accurately classifying patients [1]. We recently identified two patients presenting with rapidly fatal PH of unknown aetiology, who were subsequently diagnosed at post mortem with pulmonary tumour thrombotic microangiopathy (PTTM). This is a rare, albeit likely under-diagnosed cause of PH, characterised by a remodelling pulmonary vasculopathy rather than simple tumoural obstruction. At present, it is unclear where PTTM fits within the current classification system.PTTM is a rare, likely under-diagnosed cause of PH, which is related to, but distinct from PTE http://ow.ly/OQad5 ER -