Supplementary material

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Diagnostic test methods
Figure S1 - Nasal nitric oxide (nNO) results for n=267 PCD-negative, n=34 PCD-positive and n=8 valid-inconclusive (VI) patients. nNO mean (±SD): PCD-negative 172 nL/min (94); PCD-positive 17 nL/min (20); and VI patients 110 nL/min (119). One-way ANOVA, p<0.0001.
Figure S2 - Individual mean ciliary beat frequency (CBF) values for samples from PCD-negative and PCD-positive and valid-inconclusive (VI) patients. Group mean (±SD): a) nasal brushing biopsies: PCD-negative = 15.4 Hz (2.3), n=554; PCD-positive = 2.3 Hz (5.2), n=29; and VI = 15.6 Hz (2.7), n=8; and b) following air-liquid interface (ALI) culture; PCD-negative = 14.1 Hz (2.3), n=116; PCD-positive = 2.4 Hz (4.2), n=19; and VI = 11.7 Hz (6.3), n=6. One way ANOVA, p<0.0001.
Table S1
Table S2

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