Supplementary material

Supplementary material

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  • Figure S1 - Effect of pharmacological inhibitors on MDM phagocytosis of E. coli. MDM were generated from non-smokers (open bars), n=4-6, smokers (hatched bars), n=4-6 and COPD patients (solid bars), n=5-11, and exposed to the PI3 kinase inhibitor, LY-294001 (panel A) and the Rho kinase inhibitor, Y-27632 (panel B) or the p38 inhibitor, SB203580 (panel C) prior to exposure to FITC-labelled E. coli. Data are presented as % of the response of MDM in the absence of the inhibitor (100%) and as mean&0177;SEM.