Supplementary material
Supplementary material
Files in this Data Supplement:
- Supplementary material -
Appendix S1: Affiliations of the members of the GenPhenReSa Consortium
Appendix S2: Patient recruitment and phenotyping
Appendix S3: SNP genotyping with the Affymetrix 100k Gene Chip Array
Appendix S4: Selection criteria of SNPs for validation and fine mapping
Appendix S5: SNPlex and TaqMan genotyping
Appendix S6: Statistical analysis
Appendix S7: Analysis of tissue-specific expression by RT-PCR
Appendix S8: Bronchoalveolar lavage
Appendix S9: mRNA isolation and real-time PCR
Appendix S10: eQTL anaylsis
Table S1: Summary of GWAS (panel A) and validation (panel B) results for the top 25 SNPs that were followed up
Table S2: Results of the fine mapping stage (panel C)
Table S3: Results of additional fine mapping
Figure S1: Signal intensity/cluster plots
Figure S2: Workflow diagram summarizing the different stages of the experiment including specification of quality control parameters and selection criteria
Figure S3: Power calculation
Figure S4: Genome-wide scan of sarcoidosis (panel A)
Figure S5A-7C: Results of the eQTL analysis for the three most significant associated SNPs: rs7756421 (Figures S5A-C), rs1044670 (Figures S6A-C) and the significantly associated non-synonymous SNP rs1040461 (Figure S7A-C)
Web Resources
Supplementary References