Supplementary material

Supplementary material

Files in this Data Supplement:

• Supplementary material -
  Appendix S1: Affiliations of the members of the GenPhenReSa Consortium
  Appendix S2: Patient recruitment and phenotyping
  Appendix S3: SNP genotyping with the Affymetrix 100k Gene Chip Array
  Appendix S4: Selection criteria of SNPs for validation and fine mapping
  Appendix S5: SNPlex and TaqMan genotyping
  Appendix S6: Statistical analysis
  Appendix S7: Analysis of tissue-specific expression by RT-PCR
  Appendix S8: Bronchoalveolar lavage
  Appendix S9: mRNA isolation and real-time PCR
  Appendix S10: eQTL anaylsis
  Table S1: Summary of GWAS (panel A) and validation (panel B) results for the top 25 SNPs that were followed up
  Table S2: Results of the fine mapping stage (panel C)
  Table S3: Results of additional fine mapping
  Figure S1: Signal intensity/cluster plots
  Figure S2: Workflow diagram summarizing the different stages of the experiment including specification of quality control parameters and selection criteria
  Figure S3: Power calculation
  Figure S4: Genome-wide scan of sarcoidosis (panel A)
  Figure S5A-7C: Results of the eQTL analysis for the three most significant associated SNPs: rs7756421 (Figures S5A-C), rs1044670 (Figures S6A-C) and the significantly associated non-synonymous SNP rs1040461 (Figure S7A-C)
  Web Resources
  Supplementary References