Nationwide cloud-based integrated database of idiopathic interstitial pneumonias for multidisciplinary discussion
- Tomoyuki Fujisawa1⇑,
- Kazutaka Mori1,
- Masashi Mikamo1,
- Takashi Ohno2,
- Kensuke Kataoka3,
- Chikatoshi Sugimoto4,
- Hideya Kitamura5,
- Noriyuki Enomoto1,
- Ryoko Egashira6,
- Hiromitsu Sumikawa7,
- Tae Iwasawa8,
- Shoichiro Matsushita9,
- Hiroaki Sugiura10,
- Mikiko Hashisako11,
- Tomonori Tanaka12,
- Yasuhiro Terasaki13,
- Shinobu Kunugi13,
- Masashi Kitani14,
- Ryo Okuda5,
- Yasuoki Horiike1,
- Yasunori Enomoto1,
- Hideki Yasui1,
- Hironao Hozumi1,
- Yuzo Suzuki1,
- Yutaro Nakamura1,
- Junya Fukuoka15,
- Takeshi Johkoh16,
- Yasuhiro Kondoh3,
- Takashi Ogura5,
- Yoshikazu Inoue4,
- Yoshinori Hasegawa17,
- Naohiko Inase18,
- Sakae Homma19 and
- Takafumi Suda1
- 1Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan
- 2Esite Healthcare Co., Ltd., Tokyo, Japan
- 3Department of Respiratory Medicine and Allergy, Tosei General Hospital, Seto, Japan
- 4Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan
- 5Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
- 6Department of Radiology, Faculty of Medicine, Saga University, Saga, Japan
- 7Department of Radiology, Sakai City Medical Center, Sakai, Japan
- 8Department of Radiology, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
- 9Department of Radiology, St.Marianna University School of Medicine, Kawasaki, Japan
- 10Department of Radiology, Keio University School of Medicine, Tokyo, Japan
- 11Division of Diagnostic Pathology, Kyushu University Hospital, Fukuoka, Japan
- 12Department of Pathology, Kindai University Faculty of Medicine, Osaka, Japan
- 13Department of Analytic Human Pathology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan
- 14Department of Pathology, National Hospital Organization Tokyo National Hospital, Tokyo, Japan
- 15Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
- 16Department of Radiology, Kinki Central Hospital of Mutual Aid Association of Public-School Teachers, Itami, Japan
- 17Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
- 18Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, Japan
- 19Department of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, Japan
- Tomoyuki Fujisawa, 1-20-1 Handayama Higashi-ku, Hamamatsu 431-3192, Japan. E-mail: fujisawa{at}hama-med.ac.jp
Abstract
Multidisciplinary discussion (MDD) requiring close communication between specialists (clinicians, radiologists, and pathologists) is the gold standard for the diagnosis of idiopathic interstitial pneumonias (IIPs). However, MDD by specialists is not always feasible because they are often separated by time and location. An online database would facilitate data sharing and MDD. Our aims were to develop a nationwide cloud-based integrated database containing the clinical, radiologic, and pathological data of patients with IIPs along with a web-based MDD system and to validate the diagnostic utility of web-based MDD in IIPs.
Clinical data, high-resolution computed tomography images, and lung biopsy slides from patients with IIPs were digitised and uploaded to separate servers to develop a cloud-based integrated database. Web-based MDD was performed using the database and video-conferencing to reach a diagnosis.
The clinical, radiologic, and pathological data of 524 patients in 39 institutions were collected, uploaded, and incorporated into the cloud-based integrated database. Subsequently, web-based MDD with a pulmonologist, radiologist, and pathologist using the database and video conferencing were successfully performed for the 465 cases with adequate data. Overall, the web-based MDD changed the institutional diagnosis in 219 cases (47%). Notably, the MDD diagnosis yielded better prognostic separation among the IIPs than did the institutional diagnosis.
This is the first study of developing nationwide cloud-based integrated database containing the clinical, radiologic, and pathological data for web-based MDD in patients with IIPs. The database and the web-based MDD system that we built made MDD more feasible in practice, potentially increasing accurate diagnosis of IIPs.
Footnotes
This manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.
Conflict of interest: Dr. Fujisawa has nothing to disclose.
Conflict of interest: Dr. Mori has nothing to disclose.
Conflict of interest: Dr. Mikamo has nothing to disclose.
Conflict of interest: Dr. Ohno has nothing to disclose.
Conflict of interest: Dr. Kataoka has nothing to disclose.
Conflict of interest: Dr. Sugimoto has nothing to disclose.
Conflict of interest: Dr. Kitamura has nothing to disclose.
Conflict of interest: Dr. Enomoto has nothing to disclose.
Conflict of interest: Dr. EGASHIRA has nothing to disclose.
Conflict of interest: Dr. Sumikawa has nothing to disclose.
Conflict of interest: Dr. Iwasawa has nothing to disclose.
Conflict of interest: Dr. Matsushita has nothing to disclose.
Conflict of interest: Dr. Sugiura reports and receives honorarai for consultancy services from Ono Pharmaceutical Co., Ltd, Bristol-Myers Squibb K. K., and MSD K. K..
Conflict of interest: Dr. Hashisako has nothing to disclose.
Conflict of interest: Dr. TANAKA has nothing to disclose.
Conflict of interest: Yasuhiro Terasaki
Conflict of interest: Dr. Kunugi has nothing to disclose.
Conflict of interest: Dr. Kitani has nothing to disclose.
Conflict of interest: Dr. Okuda has nothing to disclose.
Conflict of interest: Dr. Horiike has nothing to disclose.
Conflict of interest: Dr. Yasui has nothing to disclose.
Conflict of interest: Dr. Hozumi has nothing to disclose.
Conflict of interest: Dr. Suzuki has nothing to disclose.
Conflict of interest: Dr. Nakamura has nothing to disclose.
Conflict of interest: Dr. Fukuoka has nothing to disclose.
Conflict of interest: Dr. Johkoh has nothing to disclose.
Conflict of interest: Dr. Kondoh has nothing to disclose.
Conflict of interest: Dr. Ogura has nothing to disclose.
Conflict of interest: Dr. Inoue reports other from Boehringer Ingelheim, outside the submitted work.
Conflict of interest: Dr. Hasegawa has nothing to disclose.
Conflict of interest: Dr. Inase has nothing to disclose.
Conflict of interest: Dr. Homma has nothing to disclose.
Conflict of interest: Dr. Suda has nothing to disclose.
This is a PDF-only article. Please click on the PDF link above to read it.
- Copyright ©ERS 2019