Development and validation of a simple tool for the assessment of home NIV: the S3-NIV questionnaire
- Elise Dupuis-Lozeron1,
- Grégoire Gex2,3,
- Patrick Pasquina3,
- Pierre-Olivier Bridevaux2,3,5,
- Jean-Christian Borel4,
- Paola Gasche-Soccal3,5,
- Wolfram Windisch6,
- Jean-Louis Pépin7,8,
- Jean-Paul Janssens3,5 and
- Dan Adler3,5
- 1Division of Clinical Epidemiology, Geneva University Hospitals, Geneva, Switzerland
- 2Division of Lung Diseases, Hôpital du Valais, Sion, Switzerland
- 3Division of Lung Diseases, Geneva University Hospitals, Geneva, Switzerland
- 4AgirADom, Grenoble, France
- 5University of Geneva Medical School, Geneva, Switzerland
- 6Cologne Merheim Hospital, Department of Pneumology, Kliniken der Stadt Köln, Witten/Herdecke University, Faculty of Health/School of Medicine, Germany
- 7HP2 Laboratory, Inserm U1042 Unit, Grenoble Alps University, Grenoble, France
- 8EFCR Laboratory, Thorax and Vessels, Grenoble Alps University Hospital, Grenoble, France
- Dan Adler, MD, Division of Pulmonary Diseases, Geneva University Hospitals, 4 Rue Gabrielle Perret-Gentil, 1211 Geneva 14/Switzerland. E-mail: dan.adler{at}hcuge.ch
Abstract
Patient-centered outcomes are significantly modified by long-term home non-invasive ventilation (NIV), but a short, self-administered, specific tool for routine clinical assessment is lacking. The aim of this study was to develop and validate the S3-NIV questionnaire, a short questionnaire to measure respiratory symptoms, sleep quality and NIV-related side-effects.
Stable patients under long-term home NIV were recruited from three outpatient NIV services. Questionnaire development consisted of a selection of core items for analysis, followed by item reduction, validation and test-retest reliability.
338 patients completed a 22-item questionnaire. Eleven items were removed because of non-scalability (n=2), redundancy (n=8) and lack of fit (n=1). The final version of the S3-NIV questionnaire consisted of 11 items covering two dimensions: “respiratory symptoms” (Cronbach alpha=0.84) and “sleep & NIV-related side-effects” (Cronbach alpha=0.77). Convergent validity was high between the “respiratory symptoms” subscale of the S3-NIV questionnaire and the St. George's Respiratory Questionnaire (rho=−0.76; p<0.001), as well as the “sleep & NIV side-effects” subscale and the Quebec Sleep Questionnaire (rho=0.51; p<0.001). The S3-NIV questionnaire had a good test-retest reliability after 4 weeks (intraclass correlation coefficient=0.72).
The S3-NIV questionnaire is a short, valid and repeatable, self-completed tool for the routine clinical assessment of patients undergoing home NIV.
Footnotes
This manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.
Elise Dupuis-Lozeron
Grégoire Gex
Patrick Pasquina
Olivier Bridevaux
Christian Borel
Paola Gasche-Soccal
Wolfram Windisch
Conflict of interest: Dr. Pépin has nothing to disclose.
Paul JanBens
Conflict of interest: Dr. Adler has nothing to disclose.
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