Extract
In terms of previous experience, endoscopy plays a leading role in diagnosis of early central lung cancer, which rapidly and effectively detects changes of tracheobronchial tree mucosa at the initial stages of carcinogenesis [1]. Nevertheless, the most recent SLEEPREBB trail published in European Respiratory Journal [2] has revealed that intensive bronchoscopy surveillance using AFI (autofluorescence imaging) in patients with mild or moderate dysplasia did not improve their outcomes for developing lung cancer at long term. 13 patients (3.6%) had developed a persistent CIS (carcinoma in situ) or an invasive lung cancer in this randomized prospective multicenter study during 36 months follow-up, 8 of them were with a minor or moderate dysplasia at baseline, but preventive local treatment or follow-up did not significantly affect the outcome.
Footnotes
This manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.
Conflict of interest: The authors declare no competing interests.
- Received July 11, 2021.
- Accepted December 10, 2022.
- Copyright ©The authors 2022. For reproduction rights and permissions contact permissions{at}ersnet.org