Extract
Tuberculosis (TB) is the world-leading cause of infectious disease related mortality, apart from COVID-19 presently [1]. Standard TB treatment for drug-susceptible (DS) TB takes 6–9 months and requires daily intake of multiple medications [1]. Notably, proper treatment adherence is essential for successful treatment outcome [1, 2]. To improve adherence, counseling and education are important. For specific patient groups, such as those with drug-resistant TB, HIV co-infection and those on intermittent treatment regiments, the World Health Organization (WHO) advises to use the Directly Observed Treatment (DOT) strategy. However, even with DOT, treatment completion is still challenging and cure rates and outcomes remain suboptimal [3].
Footnotes
This manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.
Conflict of interest: All authors report smart pill bottles provided free of charge by Pill Connect/eLucid mHealth, along with grant payments made to institution, supporting the present work.
Conflict of interest: Daan J. Touw reports grants from Chiesi Pharmaceuticals; consulting fees from PureIMS; lecture honoraria from PAO Farmacie; participation on a Data Safety Monitoring Board for the FORMAT trial, and participation on an advisory board for Sanquin, outside the submitted work.
Conflict of interest: Mathieu S. Bolhuis reports consulting fees from Pfizer, Kinderformularium, Pediatric formulary Netherlands; lecture honoraria from PAO Farmacie; outside the submitted work.
Conflict of interest: All other authors have nothing else to disclose.
- Received August 29, 2022.
- Accepted October 14, 2022.
- Copyright ©The authors 2022. For reproduction rights and permissions contact permissions{at}ersnet.org
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