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History
- Received June 18, 2021
- Accepted October 28, 2021
- Published online November 25, 2021.
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Copyright ©The authors 2021. This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org
Author Information
- Stacey N. Reinke1,2,30,
- Shama Naz1,30,
- Romanas Chaleckis1,3,
- Hector Gallart-Ayala1,
- Johan Kolmert1,4,
- Nazanin Z. Kermani5,
- Angelica Tiotiu5,6,
- David I. Broadhurst2,
- Anders Lundqvist7,
- Henric Olsson8,
- Marika Ström9,10,
- Åsa M. Wheelock9,10,
- Cristina Gómez1,4,
- Magnus Ericsson11,
- Ana R. Sousa12,
- John H. Riley12,
- Stewart Bates12,
- James Scholfield13,
- Matthew Loza14,
- Frédéric Baribaud14,
- Per S. Bakke15,
- Massimo Caruso16,
- Pascal Chanez17,
- Stephen J. Fowler18,
- Thomas Geiser19,
- Peter Howarth13,
- Ildikó Horváth20,
- Norbert Krug21,
- Paolo Montuschi22,
- Annelie Behndig23,
- Florian Singer24,
- Jacek Musial25,
- Dominick E. Shaw26,
- Barbro Dahlén10,
- Sile Hu27,
- Jessica Lasky-Su28,
- Peter J. Sterk29,
- Kian Fan Chung5,
- Ratko Djukanovic13,
- Sven-Erik Dahlén4,10,
- Ian M. Adcock5 and
- Craig E. Wheelock1,3,10⇑
- on behalf of the U-BIOPRED Study Group#
- 1Division of Physiological Chemistry 2, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
- 2Centre for Integrative Metabolomics & Computational Biology, School of Science, Edith Cowan University, Perth, Australia
- 3Gunma Initiative for Advanced Research (GIAR), Gunma University, Maebashi, Japan
- 4The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
- 5National Heart and Lung Institute, Imperial College, London, U.K
- 6Department of Pulmonology, University Hospital of Nancy, Nancy, France
- 7Respiratory & Immunology, BioPharmaceuticals R&D, DMPK, Research and Early Development, AstraZeneca, Gothenburg, Sweden
- 8Translational Science and Experimental Medicine, Research and Early Development, AstraZeneca, Gothenburg, Sweden
- 9Respiratory Medicine Unit, K2 Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
- 10Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden
- 11Department of Clinical Pharmacology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
- 12Glaxo Smith Kline, London, U.K
- 13Faculty of Medicine, Southampton University and NIHR Southampton Respiratory Biomedical Research Center, University Hospital Southampton, Southampton, U.K
- 14Janssen Research and Development, High Wycombe, U.K
- 15Institute of Medicine, University of Bergen, Bergen, Norway
- 16Department of Biomedical and Biotechnological Sciences and Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy
- 17Assistance Publique des Hôpitaux de Marseille, Clinique des Bronches, Allergies et Sommeil, Aix Marseille Université, Marseille, France
- 18Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, and Manchester Academic Health Science Centre and NIHR Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester, U.K
- 19Department of Pulmonary Medicine, University Hospital, University of Bern, Switzerland
- 20Department of Pulmonology, Semmelweis University, Budapest, Hungary
- 21Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany
- 22Pharmacology, Catholic University of the Sacred Heart, Rome, Italy
- 23Department of Public Health and Clinical Medicine, Section of Medicine, Umeå University, Umeå, Sweden
- 24Division of Paediatric Respiratory Medicine and Allergology, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Switzerland
- 25Dept of Medicine, Jagiellonian University Medical College, Krakow, Poland
- 26Nottingham NIHR Biomedical Research Centre, University of Nottingham, U.K
- 27Data Science Institute, Imperial College, London, U.K
- 28Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
- 29Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
- 30equal contribution
- Craig Wheelock (craig.wheelock{at}ki.se)
Funding
Konsul Th C Berghs Stiftelse
ChAMP (Centre for Allergy Research Highlights Asthma Markers of Phenotype) consortium
Hjärt-Lungfonden
HLF 20180290Stockholms Läns Landsting
Stiftelsen för Strategisk Forskning
Canadian Institutes of Health Research
MFE-135481Innovative Medicines Initiative
no. 115010Vårdalstiftelsen
Vetenskapsrådet
2014-3281; 2016-02798; 2016-0338