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Identification of asthma associated microRNAs in bronchial biopsies

Mirjam P. Roffel, Ilse M. Boudewijn, Jos L.L. van Nijnatten, Alen Faiz, Corneel J. Vermeulen, Antoon J. van Oosterhout, Karen Affleck, Wim Timens, Ken R. Bracke, Tania Maes, Irene H. Heijink, Corry-Anke Brandsma, Maarten van den Berge
European Respiratory Journal 2021; DOI: 10.1183/13993003.01294-2021
Mirjam P. Roffel
1Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
3Department of Respiratory Medicine, Ghent University, University Hospital Ghent, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent, Belgium
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Ilse M. Boudewijn
2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
4Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Jos L.L. van Nijnatten
1Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
5Faculty of Science, Respiratory Bioinformatics and Molecular Biology (RBMB), University of Technology Sydney, Sydney, Australia
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Alen Faiz
1Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
5Faculty of Science, Respiratory Bioinformatics and Molecular Biology (RBMB), University of Technology Sydney, Sydney, Australia
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Corneel J. Vermeulen
2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
4Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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  • ORCID record for Corneel J. Vermeulen
Antoon J. van Oosterhout
6Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Stevenage, United Kingdom
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Karen Affleck
7Adaptive Immunity Research Unit, GlaxoSmithKline, Stevenage, United Kingdom
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Wim Timens
1Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
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  • ORCID record for Wim Timens
Ken R. Bracke
3Department of Respiratory Medicine, Ghent University, University Hospital Ghent, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent, Belgium
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Tania Maes
3Department of Respiratory Medicine, Ghent University, University Hospital Ghent, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent, Belgium
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Irene H. Heijink
1Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
4Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Corry-Anke Brandsma
1Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
8Both senior authors contributed equally
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Maarten van den Berge
2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
4Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
8Both senior authors contributed equally
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  • For correspondence: m.van.den.berge@umcg.nl
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Article Information

DOI 
https://doi.org/10.1183/13993003.01294-2021
PubMed 
34446467

Published By 
European Respiratory Society
Print ISSN 
0903-1936
Online ISSN 
1399-3003
History 
  • Received May 5, 2021
  • Accepted July 30, 2021
  • Published online August 26, 2021.

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  • You are currently viewing a previous version of this article (August 26, 2021 - 07:51).
  • View the most recent version of this article
Copyright & Usage 
Copyright ©The authors 2021. For reproduction rights and permissions contact permissions@ersnet.org

Author Information

  1. Mirjam P. Roffel1,2,3,
  2. Ilse M. Boudewijn2,4,
  3. Jos L.L. van Nijnatten1,2,5,
  4. Alen Faiz1,2,5,
  5. Corneel J. Vermeulen2,4,
  6. Antoon J. van Oosterhout6,
  7. Karen Affleck7,
  8. Wim Timens1,2,
  9. Ken R. Bracke3,
  10. Tania Maes3,
  11. Irene H. Heijink1,2,4,
  12. Corry-Anke Brandsma1,2,8 and
  13. Maarten van den Berge2,4,8⇑
  1. 1Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  2. 2University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
  3. 3Department of Respiratory Medicine, Ghent University, University Hospital Ghent, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent, Belgium
  4. 4Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  5. 5Faculty of Science, Respiratory Bioinformatics and Molecular Biology (RBMB), University of Technology Sydney, Sydney, Australia
  6. 6Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Stevenage, United Kingdom
  7. 7Adaptive Immunity Research Unit, GlaxoSmithKline, Stevenage, United Kingdom
  8. 8Both senior authors contributed equally
  1. Maarten van den Berge (m.van.den.berge{at}umcg.nl)
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Funding

  • Bijzonder Onderzoeksfonds

    05U40516
  • Ministerie van Economische Zaken en Klimaat

  • GlaxoSmithKline

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Identification of asthma associated microRNAs in bronchial biopsies
Mirjam P. Roffel, Ilse M. Boudewijn, Jos L.L. van Nijnatten, Alen Faiz, Corneel J. Vermeulen, Antoon J. van Oosterhout, Karen Affleck, Wim Timens, Ken R. Bracke, Tania Maes, Irene H. Heijink, Corry-Anke Brandsma, Maarten van den Berge
European Respiratory Journal Jan 2021, 2101294; DOI: 10.1183/13993003.01294-2021

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Identification of asthma associated microRNAs in bronchial biopsies
Mirjam P. Roffel, Ilse M. Boudewijn, Jos L.L. van Nijnatten, Alen Faiz, Corneel J. Vermeulen, Antoon J. van Oosterhout, Karen Affleck, Wim Timens, Ken R. Bracke, Tania Maes, Irene H. Heijink, Corry-Anke Brandsma, Maarten van den Berge
European Respiratory Journal Jan 2021, 2101294; DOI: 10.1183/13993003.01294-2021
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