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Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study

Alyn Morice, Jaclyn A. Smith, Lorcan McGarvey, Surinder S. Birring, Sean M. Parker, Alice Turner, Thomas Hummel, Isabella Gashaw, Lueder Fels, Stefan Klein, Klaus Francke, Christian Friedrich
European Respiratory Journal 2021; DOI: 10.1183/13993003.04240-2020
Alyn Morice
1Respiratory Research Group, Hull York Medical School, University of Hull, Hull, UK
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  • For correspondence: a.h.morice@hull.ac.uk
Jaclyn A. Smith
2Manchester University NHS Foundation Trust, and Manchester Academic Health Science Centre, Manchester, UK
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Lorcan McGarvey
3Wellcome Wolfson Institute of Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
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Surinder S. Birring
4Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College Hospital, London, UK
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Sean M. Parker
5North Tyneside Hospital, Northumbria Healthcare NHS Foundation Trust, North Shields, UK
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Alice Turner
6Institute of Applied Health Research and Population Sciences, University of Birmingham, Birmingham, UK
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Thomas Hummel
7Smell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany
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Isabella Gashaw
8Bayer AG, Berlin, Germany
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Lueder Fels
8Bayer AG, Berlin, Germany
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Stefan Klein
8Bayer AG, Berlin, Germany
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Klaus Francke
8Bayer AG, Berlin, Germany
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Christian Friedrich
8Bayer AG, Berlin, Germany
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Article Information

DOI 
https://doi.org/10.1183/13993003.04240-2020
PubMed 
33986030

Published By 
European Respiratory Society
Print ISSN 
0903-1936
Online ISSN 
1399-3003
History 
  • Received November 17, 2020
  • Accepted April 5, 2021
  • Published online May 13, 2021.

Copyright & Usage 
Copyright ©The authors 2021. For reproduction rights and permissions contact permissions@ersnet.org

Author Information

  1. Alyn Morice1⇑,
  2. Jaclyn A. Smith2,
  3. Lorcan McGarvey3,
  4. Surinder S. Birring4,
  5. Sean M. Parker5,
  6. Alice Turner6,
  7. Thomas Hummel7,
  8. Isabella Gashaw8,
  9. Lueder Fels8,
  10. Stefan Klein8,
  11. Klaus Francke8 and
  12. Christian Friedrich8
  1. 1Respiratory Research Group, Hull York Medical School, University of Hull, Hull, UK
  2. 2Manchester University NHS Foundation Trust, and Manchester Academic Health Science Centre, Manchester, UK
  3. 3Wellcome Wolfson Institute of Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
  4. 4Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College Hospital, London, UK
  5. 5North Tyneside Hospital, Northumbria Healthcare NHS Foundation Trust, North Shields, UK
  6. 6Institute of Applied Health Research and Population Sciences, University of Birmingham, Birmingham, UK
  7. 7Smell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany
  8. 8Bayer AG, Berlin, Germany
  1. Alyn Morice, Respiratory Research Group, Hull York Medical School, University of Hull, Cottingham, Hull, East Yorkshire, HU16 5JQ, UK. E-mail: a.h.morice{at}hull.ac.uk
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Funding

  • Bayer

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Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study
Alyn Morice, Jaclyn A. Smith, Lorcan McGarvey, Surinder S. Birring, Sean M. Parker, Alice Turner, Thomas Hummel, Isabella Gashaw, Lueder Fels, Stefan Klein, Klaus Francke, Christian Friedrich
European Respiratory Journal Jan 2021, 2004240; DOI: 10.1183/13993003.04240-2020

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Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study
Alyn Morice, Jaclyn A. Smith, Lorcan McGarvey, Surinder S. Birring, Sean M. Parker, Alice Turner, Thomas Hummel, Isabella Gashaw, Lueder Fels, Stefan Klein, Klaus Francke, Christian Friedrich
European Respiratory Journal Jan 2021, 2004240; DOI: 10.1183/13993003.04240-2020
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