Extract
A number of antigen-detecting rapid diagnostic tests (Ag-RDTs) for SARS-CoV-2 are now commercially available and can result in rapid decisions on patient care, isolation and contact tracing at the point-of-care [1]. Two Ag-RDTs using nasopharyngeal (NP) swab samples meet WHO targets and are now approved through the WHO Emergency Use Listing procedure [2–4].
Acknowledgements
Heike Rössig, Chiara Manon Rohardt, Claudia Hülso, Elisabeth Linzbach, Susen Burock, Katja von dem Busche, Stephanie Padberg, Melanie Bothmann, Zümrüt Tuncer, Stefanie Lunow, Beate Zimmer, Astrid Barrera Pesek, Sabrina Pein, Nicole Buchholz, Verena Haack, Oliver Deckwart.
Footnotes
Data availability: Available data; - De-identified data that underlie the results in this paper - Study protocol- Analysis code Until 5 years after publication Available to: researchers who provide a sound proposal and all study sites agree to sharing the data Proposals should be directed towards the corresponding author
Author contributions: AKL, LJK, FL and CMD designed the study and developed standard operating procedures. AKL and ON implemented the study design, enrolled patients, performed laboratory work and led the writing of the manuscript. FPM and JS coordinated and supervised the study site. FK, MW, FH enrolled patients. MGe coordinated the testing facility. MGa, LK and FT led the data analysis. VC, JH and CD were responsible for PCR testing and contributed to the interpretation of the data. JAS supported the study design setup and the interpretation of the data. CMD was the principle investigator of the study. All authors have reviewed the manuscript.
Support statement: The study was supported by FIND, Heidelberg University Hospital and Charité University Hospital internal funds, as well as a grant of the Ministry of Science, Research and the Arts of Baden-Württemberg, Germany. FIND provided input on the study design, and data analysis in collaboration with the rest of the study team. Ministry of Science, Research and the Arts of Baden-Württemberg, Germany; FIND; Charité Universitätsmedizin Berlin; DOI: http://dx.doi.org/10.13039/501100002839; Grant: internal funds; Heidelberg University Hospital; Grant: internal funds.
Conflict of interest: Dr. Lindner has nothing to disclose.
Conflict of interest: Mrs. Nikolai has nothing to disclose.
Conflict of interest: Mrs. Kausch has nothing to disclose.
Conflict of interest: Mrs. Wintel has nothing to disclose.
Conflict of interest: Dr. Hommes has nothing to disclose.
Conflict of interest: Dr. Gertler has nothing to disclose.
Conflict of interest: Dr. Gaeddert has nothing to disclose.
Conflict of interest: Mr. Tobian has nothing to disclose.
Conflict of interest: Dr. Lainati has nothing to disclose.
Conflict of interest: Lisa Köppel has nothing to disclose.
Conflict of interest: Dr. Seybold has nothing to disclose.
Conflict of interest: Dr. Corman has nothing to disclose.
Conflict of interest: Dr. Drosten has nothing to disclose.
Conflict of interest: Dr. Hofmann has nothing to disclose.
Conflict of interest: Dr. Sacks reports grants from UK Department of International Development (DFID, recently replaced by FCMO), grants from World Health Organization (WHO), grants from Unitaid, during the conduct of the study.
Conflict of interest: Dr. Mockenhaupt has nothing to disclose.
Conflict of interest: Dr. Denkinger reports grants from Foundation of Innovative Diagnostics, grants from Ministry of Science, Research and Culture, State of Baden Wuerttemberg, Germany, during the conduct of the study.
Conflict of interest: Lisa J. Krüger has nothing to disclose.
- Received October 26, 2020.
- Accepted November 24, 2020.
- Copyright ©ERS 2020
This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
