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Minimal clinically important differences for Dyspnea-12 and MDP scores are similar at 2 weeks and 6 months: follow-up of a longitudinal clinical study

Magnus Ekström, Hans Bornefalk, C. Magnus Sköld, Christer Janson, Anders Blomberg, Jacob Sandberg, Anna Bornefalk-Hermansson, David C Currow, Miriam J Johnson, Josefin Sundh
European Respiratory Journal 2020; DOI: 10.1183/13993003.02823-2020
Magnus Ekström
1Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund, Sweden
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  • ORCID record for Magnus Ekström
  • For correspondence: pmekstrom@gmail.com
Hans Bornefalk
2Hans Bornefalk AB, Vallentuna, Sweden
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C. Magnus Sköld
3Respiratory Medicine Unit, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
4Department of Respiratory Medicine and Allergy, Karolinska University Hospital Solna, Stockholm, Sweden
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Christer Janson
5Department of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden
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  • ORCID record for Christer Janson
Anders Blomberg
6Department of Public Health and Clinical Medicine, Section of Medicine, Umeå University, Umeå, Sweden
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Jacob Sandberg
1Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund, Sweden
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Anna Bornefalk-Hermansson
7Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden
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David C Currow
8IMPACCT, Faculty of Health, University of Technology Sydney, Ultimo, Sydney, Australia
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Miriam J Johnson
9Wolfson Palliative Care Research Centre, University of Hull, Hull, UK
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Josefin Sundh
10Department of Respiratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
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Extract

Chronic breathlessness is a dominating symptom that restricts daily life for many people with cardiorespiratory disease [1]. Different dimensions of the symptom, such as the intensity, sensory qualities (SQs) and emotional responses, can be assessed using the instruments Dyspnea-12 (D-12) [2] and the Multidimensional Dyspnea Profile (MDP) [3], which share similarities in the underlying constructs of what is measured [4] and have emerged as widely used instruments for multi-dimensional measurement of breathlessness.

Footnotes

This manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.

Conflict of interest: Dr. Ekström has nothing to disclose.

Conflict of interest: Dr. Bornefalk has nothing to disclose.

Conflict of interest: Dr. Sköld has nothing to disclose.

Conflict of interest: Dr. Jansson has nothing to disclose.

Conflict of interest: Dr. Blomberg has nothing to disclose.

Conflict of interest: Dr. Sandberg has nothing to disclose.

Conflict of interest: Dr. Bornefalk-Hermansson has nothing to disclose.

Conflict of interest: Dr. Currow reports he is an unpaid advisory board member for Helsinn Pharmaceuticals. He is a paid consultant and receives payment for intellectual property with Mayne Pharma and is a consultant with Specialised Therapeutics Australia Pty. Ltd.

Conflict of interest: Dr. Johnson has nothing to disclose.

Conflict of interest: Dr. Sundh has nothing to disclose.

  • Received July 17, 2020.
  • Accepted November 5, 2020.
  • Copyright ©ERS 2020
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Minimal clinically important differences for Dyspnea-12 and MDP scores are similar at 2 weeks and 6 months: follow-up of a longitudinal clinical study
Magnus Ekström, Hans Bornefalk, C. Magnus Sköld, Christer Janson, Anders Blomberg, Jacob Sandberg, Anna Bornefalk-Hermansson, David C Currow, Miriam J Johnson, Josefin Sundh
European Respiratory Journal Jan 2020, 2002823; DOI: 10.1183/13993003.02823-2020

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Minimal clinically important differences for Dyspnea-12 and MDP scores are similar at 2 weeks and 6 months: follow-up of a longitudinal clinical study
Magnus Ekström, Hans Bornefalk, C. Magnus Sköld, Christer Janson, Anders Blomberg, Jacob Sandberg, Anna Bornefalk-Hermansson, David C Currow, Miriam J Johnson, Josefin Sundh
European Respiratory Journal Jan 2020, 2002823; DOI: 10.1183/13993003.02823-2020
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