Extract
With great interest we read and commend the study done by Russo and colleagues, highlighting their findings that nicotine induces an increase in angiotensin-converting enzyme-2 (ACE2) expression in human bronchial epithelial cells (HBEpC) and is mediated by α7-subtype nicotinic receptors (α7-nAChR) [1]. It raises the concern that all electronic nicotine-delivery systems may put users at greater risk of succumbing to COVID-19.
Acknowledgements
Clifford Craig Foundation Launceston General Hospital, Rebecca L. Cooper Medical Research Foundation.
Footnotes
Conflict of interest: Dr. McAlinden has nothing to disclose.
Conflict of interest: Dr. Eapen has nothing to disclose.
Conflict of interest: Dr. Lu has nothing to disclose.
Conflict of interest: Dr. Chia has nothing to disclose.
Conflict of interest: Dr. Haug has nothing to disclose.
Conflict of interest: Dr. Sohal has nothing to disclose.
- Received May 7, 2020.
- Accepted May 10, 2020.
- Copyright ©ERS 2020
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