Extract
Since there is an increasing number of coronavirus disease 2019 (COVID-19) cases confirmed in multiple countries around the world, resulting in alarmingly high mortality and morbidity [1], the World Health Organization (WHO) has declared a global pandemic [2]. To our knowledge, current research on COVID-19 focuses on the epidemics, its clinical features and treatment, but not on viral RNA shedding. Here, we discuss COVID-19 viral RNA conversion time and the risk factors associated with viral RNA shedding in a large patient cohort.
Abstract
The median time from symptoms onset to viral RNA shedding was 19 days. Patients with CHD comorbidity or decreased albumin levels experienced delays in clearance of SARS-CoV-2 RNA.
Acknowledgements
This study is funded by National Natural Science Foundation of China [grant number 81570501, 81770554, 81772607, 81974383] and Key Projects in the Natural Scientific and Technology Program (2018ZX10302204-002-003). We acknowledge all of the medical workers participated in the diagnosis and treatment of patients in Wuhan. We thank all the patients involved in this study.
Footnotes
Funder: National Natural Science Foundation of China; DOI: http://dx.doi.org/10.13039/501100001809; Grant: 81570501, 81770554, 81772607, 81974383; Key Projects in the Natural Scientific and Technology Program; Grant: 2018ZX10302204-002-003.
Conflict of interest: Dr. Fu has nothing to disclose.
Conflict of interest: Dr. Han has nothing to disclose.
Conflict of interest: Dr. Zhu has nothing to disclose.
Conflict of interest: Dr. Bai has nothing to disclose.
Conflict of interest: Dr. Yi has nothing to disclose.
Conflict of interest: Dr. Zhao has nothing to disclose.
Conflict of interest: Dr. Tao has nothing to disclose.
Conflict of interest: Dr. Quan has nothing to disclose.
Conflict of interest: Dr. Chen has nothing to disclose.
Conflict of interest: Dr. Zhang has nothing to disclose.
Conflict of interest: Dr. He has nothing to disclose.
Conflict of interest: Dr. Jing has nothing to disclose.
Conflict of interest: Dr. Xiong has nothing to disclose.
Conflict of interest: Dr. Tian has nothing to disclose.
Conflict of interest: Dr. Yan has nothing to disclose.
- Received April 9, 2020.
- Accepted May 2, 2020.
- Copyright ©ERS 2020
This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.