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ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19

Janice M. Leung, Chen X. Yang, Anthony Tam, Tawimas Shaipanich, Tillie-Louise Hackett, Gurpreet K. Singhera, Delbert R. Dorscheid, Don D. Sin
European Respiratory Journal 2020; DOI: 10.1183/13993003.00688-2020
Janice M. Leung
1University of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, British Columbia, Canada
2Department of Medicine (Division of Respirology), UBC, Vancouver, British Columbia, Canada
3St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada
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Chen X. Yang
1University of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, British Columbia, Canada
2Department of Medicine (Division of Respirology), UBC, Vancouver, British Columbia, Canada
3St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada
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Anthony Tam
1University of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, British Columbia, Canada
2Department of Medicine (Division of Respirology), UBC, Vancouver, British Columbia, Canada
3St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada
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Tawimas Shaipanich
2Department of Medicine (Division of Respirology), UBC, Vancouver, British Columbia, Canada
3St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada
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Tillie-Louise Hackett
2Department of Medicine (Division of Respirology), UBC, Vancouver, British Columbia, Canada
3St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada
4Department of Anesthesia, Pharmacology and Therapeutics, UBC, Vancouver, British Columbia, Canada
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Gurpreet K. Singhera
1University of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, British Columbia, Canada
2Department of Medicine (Division of Respirology), UBC, Vancouver, British Columbia, Canada
3St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada
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Delbert R. Dorscheid
1University of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, British Columbia, Canada
2Department of Medicine (Division of Respirology), UBC, Vancouver, British Columbia, Canada
3St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada
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Don D. Sin
1University of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, British Columbia, Canada
2Department of Medicine (Division of Respirology), UBC, Vancouver, British Columbia, Canada
3St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada
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Article Information

DOI 
https://doi.org/10.1183/13993003.00688-2020
PubMed 
32269089

Published By 
European Respiratory Society
Print ISSN 
0903-1936
Online ISSN 
1399-3003
History 
  • Received March 2, 2020
  • Accepted March 25, 2020
  • Published online April 8, 2020.

Article Versions

  • You are currently viewing a previous version of this article (April 8, 2020 - 16:05).
  • View the most recent version of this article
Copyright & Usage 
Copyright ©ERS 2020 This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.

Author Information

  1. Janice M. Leung1,2,3,
  2. Chen X. Yang1,2,3,
  3. Anthony Tam1,2,3,
  4. Tawimas Shaipanich2,3,
  5. Tillie-Louise Hackett2,3,4,
  6. Gurpreet K. Singhera1,2,3,
  7. Delbert R. Dorscheid1,2,3 and
  8. Don D. Sin1,2,3
  1. 1University of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, British Columbia, Canada
  2. 2Department of Medicine (Division of Respirology), UBC, Vancouver, British Columbia, Canada
  3. 3St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada
  4. 4Department of Anesthesia, Pharmacology and Therapeutics, UBC, Vancouver, British Columbia, Canada
  1. Dr Don D. Sin. E-mail: don.sin{at}hli.ubc.ca
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Funding

  • Canadian Institutes of Health Research

    FDN 332196

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ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19
Janice M. Leung, Chen X. Yang, Anthony Tam, Tawimas Shaipanich, Tillie-Louise Hackett, Gurpreet K. Singhera, Delbert R. Dorscheid, Don D. Sin
European Respiratory Journal Jan 2020, 2000688; DOI: 10.1183/13993003.00688-2020

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ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19
Janice M. Leung, Chen X. Yang, Anthony Tam, Tawimas Shaipanich, Tillie-Louise Hackett, Gurpreet K. Singhera, Delbert R. Dorscheid, Don D. Sin
European Respiratory Journal Jan 2020, 2000688; DOI: 10.1183/13993003.00688-2020
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