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Excess mucus viscosity and airway dehydration impact COPD airway clearance

Vivian Y. Lin, Niroop Kaza, Susan E. Birket, Harrison Kim, Lloyd J. Edwards, Jennifer LaFontaine, Linbo Liu, Marina Mazur, Stephen A. Byzek, Justin Hanes, Guillermo J. Tearney, S. Vamsee Raju, Steven M. Rowe
European Respiratory Journal 2019; DOI: 10.1183/13993003.00419-2019
Vivian Y. Lin
1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
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Niroop Kaza
1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
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Susan E. Birket
1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
2Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
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Harrison Kim
3Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA
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  • ORCID record for Harrison Kim
Lloyd J. Edwards
4Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA
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Jennifer LaFontaine
2Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
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Linbo Liu
2Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
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Marina Mazur
2Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
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Stephen A. Byzek
2Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
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Justin Hanes
5The Center for Nanomedicine at Wilmer Eye Institute, Johns Hopkins University, MD, USA
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Guillermo J. Tearney
6Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA
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S. Vamsee Raju
1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
2Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
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Steven M. Rowe
1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
2Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
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  • For correspondence: srrowe@uabmc.edu
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Article Information

DOI 
https://doi.org/10.1183/13993003.00419-2019
PubMed 
31672759

Published By 
European Respiratory Society
Print ISSN 
0903-1936
Online ISSN 
1399-3003
History 
  • Received February 28, 2019
  • Accepted October 9, 2019
  • Published online October 31, 2019.

Article Versions

  • You are currently viewing a previous version of this article (October 31, 2019 - 01:03).
  • View the most recent version of this article
Copyright & Usage 
Copyright ©ERS 2019

Author Information

  1. Vivian Y. Lin1,
  2. Niroop Kaza1,
  3. Susan E. Birket1,2,
  4. Harrison Kim3,
  5. Lloyd J. Edwards4,
  6. Jennifer LaFontaine2,
  7. Linbo Liu2,
  8. Marina Mazur2,
  9. Stephen A. Byzek2,
  10. Justin Hanes5,
  11. Guillermo J. Tearney6,
  12. S. Vamsee Raju1,2 and
  13. Steven M. Rowe1,2⇑
  1. 1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
  2. 2Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
  3. 3Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA
  4. 4Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA
  5. 5The Center for Nanomedicine at Wilmer Eye Institute, Johns Hopkins University, MD, USA
  6. 6Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA
  1. Dr Steven M. Rowe, MD, MSPH, 1918 University Blvd. MCLM 702, Birmingham, AL 35294. E-mail: srrowe{at}uabmc.edu
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Funding

  • National Institute of Diabetes and Digestive and Kidney Diseases

    P30DK072482
  • Flight Attendant Medical Research Institute

  • National Heart, Lung, and Blood Institute

    F31HL134225; R35HL135816

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Excess mucus viscosity and airway dehydration impact COPD airway clearance
Vivian Y. Lin, Niroop Kaza, Susan E. Birket, Harrison Kim, Lloyd J. Edwards, Jennifer LaFontaine, Linbo Liu, Marina Mazur, Stephen A. Byzek, Justin Hanes, Guillermo J. Tearney, S. Vamsee Raju, Steven M. Rowe
European Respiratory Journal Jan 2019, 1900419; DOI: 10.1183/13993003.00419-2019

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Excess mucus viscosity and airway dehydration impact COPD airway clearance
Vivian Y. Lin, Niroop Kaza, Susan E. Birket, Harrison Kim, Lloyd J. Edwards, Jennifer LaFontaine, Linbo Liu, Marina Mazur, Stephen A. Byzek, Justin Hanes, Guillermo J. Tearney, S. Vamsee Raju, Steven M. Rowe
European Respiratory Journal Jan 2019, 1900419; DOI: 10.1183/13993003.00419-2019
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