Germline BMP9 mutation causes idiopathic pulmonary arterial hypertension

From the Key Laboratory of Pulmonary Vascular Medicine & FuWai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy Medical Sciences & Peking Union Medical College (X.-J.W., X.J., T.-Y.L., S.-F.L., S.-Q.L., J.Y., C.-Y.C., Y.D., X.-Q.X., Y.W., F.-H.P., K.S., Z.-C.J.); Department of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China (W.-H.W., R.J.); Department of Respiratory Medicine, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China (Y.-M.M.); Novogene Co., Ltd., Beijing, China (H.Y., C.L.); Department of Medicine, University of California, San Diego, La Jolla, California, USA (J.S.); Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China (S.-Y. Z.) and McKusick-Zhang Center for Genetic Medicine, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (X.Z.).

Zhi-Cheng Jing, Key Laboratory of Pulmonary Vascular Medicine & FuWai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy Medical Sciences & Peking Union Medical College, No. 167, Beilishi Road, Beijing, 100037, China. E-mail: jingzhicheng{at}vip.163.com

Funding

National Key Research and Development Program of China
2016YFC0901502
National Science Fund for Distinguished Young Scholars
81425002
National Natural Science Foundation of China
81320108005; 81630003; 81670052
Director Fund from State Key Laboratory of Cardiovascular Disease
2017ZR-03; 2018ZR-02
Natural Science Foundation of Beijing Municipality
7172180; 7181009
Chinese Academy of Medical Sciences
2016-I2M-1-002; 2016-I2M-4-003