Abstract
Non-invasive ventilation (NIV) associated discomfort may participate in its failure. We aimed to determine the effect of a musical intervention on respiratory discomfort during NIV in patients with acute respiratory failure (ARF).
Three centers, open-label controlled trial; randomization of patients requiring NIV for ARF to a musical intervention (MI - receiving a MI and visual deprivation during the first 30-minutes of each NIV session); a sensory deprivation (SD - wearing an insulating headphone and visual deprivation during the first 30-minutes of each NIV session), and a control group (CG) receiving NIV as routinely performed. The primary outcome was the change in respiratory discomfort before and after 30-minutes of the first NIV session.
113 patients were randomized (39 in the CG, 36 in the MI, 38 in the SD). Median change in respiratory discomfort was 0 [−1;1] between MI and CG (p=0.7). In-between groups comparison did not evidence any significant variation of respiratory parameters across time or health-related quality of life at day-90. The Peritraumatic Distress Inventory at ICU discharge was reduced in MI-group patients.
A 30-minutes musical intervention did not reduce respiratory discomfort during NIV for ARF in comparison to conventional care or sensory deprivation.
Footnotes
This manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.
Conflict of interest: Dr. Messika reports other from Fisher&;Paykel, outside the submitted work.
Conflict of interest: Dr. Yolaine has nothing to disclose.
Conflict of interest: Dr. MAQUIGNEAU has nothing to disclose.
Conflict of interest: Dr. Puechberty has nothing to disclose.
Conflict of interest: Dr. Henry-Lagarrigue has nothing to disclose.
Conflict of interest: Dr. Stoclin has nothing to disclose.
Conflict of interest: Dr. Panneckouke has nothing to disclose.
Conflict of interest: Dr. VILLARD has nothing to disclose.
Conflict of interest: Dr. DECHANET has nothing to disclose.
Conflict of interest: Dr. Lafourcade has nothing to disclose.
Conflict of interest: Dr. Dreyfuss has nothing to disclose.
Conflict of interest: Dr. Hajage has nothing to disclose.
Conflict of interest: Dr. RICARD has nothing to disclose.
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