Disconnect between sputum neutrophils and other measures of airway inflammation in asthma

Joseph R. Arron; David F. Choy; Michel Laviolette; Steven G. Kelsen; Ammar Hatab; Richard Leigh; Neil C. Thomson; Eugene R. Bleecker; Ron Olivenstein; Pedro C. Avila; Nizar N. Jarjour; Mario Castro; Gail M. Gauvreau; James T. Good; Joel N. Kline; Adel Mansur; Irvin Mayers; Liam G. Heaney; Qutayba Hamid; Jeffrey M Harris

doi:10.1183/09031936.00117013

Disconnect between sputum neutrophils and other measures of airway inflammation in asthma

Joseph R. Arron, David F. Choy, Michel Laviolette, Steven G. Kelsen, Ammar Hatab, Richard Leigh, Neil C. Thomson, Eugene R. Bleecker, Ron Olivenstein, Pedro C. Avila, Nizar N. Jarjour, Mario Castro, Gail M. Gauvreau, James T. Good, Joel N. Kline, Adel Mansur, Irvin Mayers, Liam G. Heaney, Qutayba Hamid, Jeffrey M Harris

European Respiratory Journal 2013; DOI: 10.1183/09031936.00117013

Joseph R. Arron

*Genentech Research and Early Development, South San Francisco, CA, USA

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David F. Choy

*Genentech Research and Early Development, South San Francisco, CA, USA

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Michel Laviolette

#IUCPQ, Université Laval, Québec, QC, Canada

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Steven G. Kelsen

¶Dept of Medicine, Temple University School of Medicine, Philadelphia PA, USA

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Ammar Hatab

+West Coast Clinical Trials LLC, Costa Mesa, CA, USA

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Richard Leigh

§Faculty of Medicine, University of Calgary, Calgary, AB, Canada

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Neil C. Thomson

fInstitute of Infection, Immunity, and Inflammation, University of Glasgow, Glasgow, UK

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Eugene R. Bleecker

**Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA

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Ron Olivenstein

##Montréal Chest Institute, Montréal, QC, Canada

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Pedro C. Avila

¶¶Dept of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

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Nizar N. Jarjour

++Dept of Medicine, University of Wisconsin-Madison, Madison, WI, USA

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Mario Castro

§§Dept of Medicine, Washington University School of Medicine, St. Louis, MO, USA

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Gail M. Gauvreau

ffDept of Respirology, Faculty of Health Sciences, McMaster University, Hamilton ON, Canada

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James T. Good

***Dept of Medicine, National Jewish Health, Denver, CO

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Joel N. Kline

###Dept of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA, USA

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Adel Mansur

¶¶¶Respiratory Dept, Birmingham Heartlands Hospital, Birmingham, UK

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Irvin Mayers

+++Dept of Medicine, University of Alberta, Edmonton, AB, Canada

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Liam G. Heaney

§§§Centre for Infection and Immunity, Queens University Belfast, Belfast, UK

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Qutayba Hamid

fffMeakins-Christie Laboratories, McGill University, Montréal, QC, Canada

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Jeffrey M Harris

*Genentech Research and Early Development, South San Francisco, CA, USA

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For correspondence: harris.jeffrey@gene.com

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Disconnect between sputum neutrophils and other measures of airway inflammation in asthma

European Respiratory Journal Jan 2013, erj01170-2013; DOI: 10.1183/09031936.00117013

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Disconnect between sputum neutrophils and other measures of airway inflammation in asthma

European Respiratory Journal Jan 2013, erj01170-2013; DOI: 10.1183/09031936.00117013

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