Abstract
Background: Scallan et al.(1) proposed the R-Scale as a new questionnaire to assess the health status in patients with IPF. Objective We aimed to investigate the utility of a German version of the R-Scale (GR-Scale) by analyzing its relationship to lung function parameters in various ILD at baseline. Methods 87 patients from four different diagnostic ILD groups (see figure) completed the GR-Scale questionnaire. Pearson correlation coefficients were calculated between GR-Scale scores and routine lung function parameters (forced vital capacity (FVC) and diffusion capacity for carbon monoxide (DLco)). Results Within the entire study population, inverse correlations were found between the GR-Scale total score and FVC (r=-0.279 p=0.009) and DLco (r=-0.216 p=0.045), respectively. In group 1 (fibrotic ILD), similar negative trends existed for FVC (r=-0.33 p=0.062) and DLco (r=-0.31 p=0.075). For groups 2 (CTD-ILD) and 3 (Sarcoid) trends towards a negative correlation were found for FVC and DLco (not significant). In group 4 (cystic lung disease) FVC and the GR-Scale total score showed a positive trend (r=0.54 p=0.21).
Conclusion: Our study shows that the GR-Scale and routine lung function parameters show highly variable relationships, but also some consistent trends, thus possibly providing an additional dimension of information about the patients’ health for clinical assessment.
(1) Scallan et al. R-scale for pulmonary fibrosis. Eur Respir J 2022; 59:2100917
Footnotes
Cite this article as: European Respiratory Journal 2023; 62: Suppl. 67, PA5161.
This abstract was presented at the 2023 ERS International Congress, in session “Inflammatory endotyping: the macrophage across disease areas”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2023
