Extract
Preterm birth affects more than 15 million children born across the world each year, and complications related to prematurity are the leading cause of death in young children [1]. Those infants born extremely premature, <30 weeks gestational age (GA), are at particularly high risk of increased morbidity and mortality [2]. Bronchopulmonary dysplasia (BPD), or chronic lung disease of prematurity, impacts ∼30% of infants who were born extremely premature. BPD was first described almost 60 years ago in moderately preterm infants (∼34 weeks GA) and primarily as the result of ventilator-induced lung injury and oxygen toxicity, “old BPD” [3].
Tweetable abstract
Adult survivors of extreme preterm birth have impaired exercise tolerance with reduced oxygen consumption that appears to be related to decreased muscular fitness or alterations in oxygen delivery to the skeletal muscle. https://bit.ly/3tOBF84
Footnotes
Conflict of interest: E.B. Hysinger reports payment for expert testimony from multiple organisations, and travel support from ERS, outside the submitted work. P. Critser has nothing to disclose.
- Received October 19, 2023.
- Accepted October 20, 2023.
- Copyright ©The authors 2023. For reproduction rights and permissions contact permissions{at}ersnet.org
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