Extract
Exacerbations significantly contribute to impaired quality of life (QoL), accelerated lung function decline and premature mortality in bronchiectasis [1]. Prevention of exacerbations is one of the key goals in international guidelines for bronchiectasis [2, 3]. Thus, identifying risk factors associated with exacerbation will be important to design and deliver the right interventions to the right people, and are an active area of research [4].
Abstract
Depression was associated with an increased risk of exacerbations in patients with bronchiectasis and may be a crucial “treatable trait” for exacerbation prevention https://bit.ly/3iCwPWa
Footnotes
Author contributions: Conception and design of the study: Yong-Hua Gao, Jin-Fu Xu and Jie-Ming Qu. Data acquisition: Yong-Hua Gao, Jin-Fu Xu, Hui-Zhen Zheng, Hai-Wen Lu, Yuan-Yuan Li, Yun Feng, Bei Mao, Jiu-Wu Bai, Shuo Liang, Ke-Bin Cheng, Shu-yi Gu, Xiao-Li Sun, Jian-Xiong Li, Ai Ge, Man-Hui Li, Jia-Wei Yang, Lu Bai and Han-Yu Yu. Analysis of the data: Yong-Hua Gao, Jin-Fu Xu, Hui-Zhen Zheng, Hai-Wen Lu, Yuan-Yuan Li and Yun Feng. Yong-Hua Gao and Jin-Fu Xu drafted the initial manuscript. Yong-Hua Gao, Jin-Fu Xu and Jie-Ming Qu contributed to the data interpretation and edited the manuscript for important scientific content. All the authors agree to be accountable for all aspects of the work in regard to accuracy and integrity.
Conflict of interest: All authors have nothing to disclose.
Support statement: This work was supported by the National Natural Science Foundation of China (81925001 to Jin-Fu Xu; 82270047 to Yong-Hua Gao), Shanghai Pujiang Program (21PJD061 to Yong-Hua Gao), the Innovation Program of Shanghai Municipal Education Commission (202101070007-E00097 to Jin-Fu Xu), Program of Shanghai Municipal Science and Technology Commission (21DZ2201800 to Jin-Fu Xu), the Innovative research team of high-level local universities in Shanghai, and the Innovative team of Shanghai Pulmonary Hospital. Funding information for this article has been deposited with the Crossref Funder Registry.
- Received July 14, 2022.
- Accepted January 7, 2023.
- Copyright ©The authors 2023. For reproduction rights and permissions contact permissions{at}ersnet.org