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Risk factors for disease progression in fibrotic hypersensitivity pneumonitis

Hajime Fujimoto, Taro Yasuma, Corina N. D'Alessandro-Gabazza, Esteban C. Gabazza, Osamu Hataji, Tetsu Kobayashi
European Respiratory Journal 2023 61: 2201706; DOI: 10.1183/13993003.01706-2022
Hajime Fujimoto
1Department of Pulmonary and Critical Care Medicine, Mie University Faculty and Graduate School of Medicine, Tsu, Japan
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Taro Yasuma
2Department of Immunology, Mie University Faculty and Graduate School of Medicine, Tsu, Japan
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Corina N. D'Alessandro-Gabazza
2Department of Immunology, Mie University Faculty and Graduate School of Medicine, Tsu, Japan
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  • ORCID record for Corina N. D'Alessandro-Gabazza
Esteban C. Gabazza
2Department of Immunology, Mie University Faculty and Graduate School of Medicine, Tsu, Japan
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  • For correspondence: gabazza@doc.medic.mie-u.ac.jp
Osamu Hataji
3Respiratory Center, Matsusaka Municipal Hospital, Matsusaka, Japan
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Tetsu Kobayashi
1Department of Pulmonary and Critical Care Medicine, Mie University Faculty and Graduate School of Medicine, Tsu, Japan
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Extract

We read with great interest the article published in the European Respiratory Journal by Hambly et al. [1] on the prevalence and characteristics of progressive fibrosing interstitial lung disease (ILD) in patients diagnosed with fibrotic ILD. The study showed that half (50.1%) of 2746 patients with fibrotic ILD develop progressive fibrosing ILD within 24 months and that the prevalence of progressive fibrosing ILD is 59% in idiopathic pulmonary fibrosis, 58% in hypersensitivity pneumonitis, 51% in unclassifiable ILD and 45% in connective tissue disease-associated ILD [1].

Abstract

Awareness of the risk factors for disease progression in hypersensitivity pneumonitis will be very useful as a guide to deciding therapeutic approaches for this devastating disease in real world clinical practice https://bit.ly/3xG4B16

Footnotes

  • Author contributions: Approval and writing the correspondence draft: H. Fujimoto, T. Yasuma, C.N. D'Alessandro-Gabazza, E.C. Gabazza, O. Hataji and T. Kobayashi.

  • Conflict of interest: H. Fujimoto reports grants from Chugai, Pfizer, ONO, TAIHO, Boehringer Ingelheim and Eli Lilly, outside the submitted work. T. Yasuma reports grants from Shionogi, outside the submitted work. C.N. D'Alessandro-Gabazza reports grants from Shionogi Pharmaceutical Inc., Astellas Pharmaceuticals Inc. and Asahi Kassei, outside the submitted work. E.C. Gabazza reports grants from Shionogi Pharmaceutical Inc., Astellas Pharmaceuticals Inc. and Asahi Kassei, outside the submitted work. O. Hataji reports grants from Janssen Pharmaceutical, Chugai Pharmaceutical, Eli Lilly, Fukuda Denshi and Kyorin Pharmaceutical, grants and personal fees from AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Merk Sharp & Dohme (MSD), Novartis, Ono Pharmaceutical, Sanofi Pharmaceutical and Takeda Pharmaceutical, personal fees from Mitsubishi Tanabe Pharma, Nippon Kayaku, Nippon Chemiphar and Taiho Pharmaceutical, outside the submitted work. T. Kobayashi reports grants and personal fees from Chugai, Pfizer, ONO, Boehringer Ingelheim and Eli Lilly, grants from TAIHO, outside the submitted work.

  • Received August 31, 2021.
  • Accepted September 15, 2022.
  • Copyright ©The authors 2023. For reproduction rights and permissions contact permissions{at}ersnet.org
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Risk factors for disease progression in fibrotic hypersensitivity pneumonitis
Hajime Fujimoto, Taro Yasuma, Corina N. D'Alessandro-Gabazza, Esteban C. Gabazza, Osamu Hataji, Tetsu Kobayashi
European Respiratory Journal Jan 2023, 61 (1) 2201706; DOI: 10.1183/13993003.01706-2022

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Risk factors for disease progression in fibrotic hypersensitivity pneumonitis
Hajime Fujimoto, Taro Yasuma, Corina N. D'Alessandro-Gabazza, Esteban C. Gabazza, Osamu Hataji, Tetsu Kobayashi
European Respiratory Journal Jan 2023, 61 (1) 2201706; DOI: 10.1183/13993003.01706-2022
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