Abstract
Introduction: The aim was to analyze the clinical and prognostic differences between patients with PE with home and hospital treatment.
Methods: The RIETE registry included 18145 and 1166 PE patients treated at hospital and at home. The clinical features were compared according to the treatment regimen.
Results: Patients with home therapy were younger than patients treated at hospital (59.0±16.4 vs 66.8±17.2 years, p<0.001), presented less immobilization (15% vs 19%, OR 0.75, 95%CI 0.64-0.88) and had less unprovoked PE (50% vs 55%, OR 0.80, 95%CI 0.71-0.90), had more subsegmental PE (17% vs 4.6%, OR 4.17, 95%CI 3.42-5.09) and less proximal PE (16% vs 43%), OR 0.26, 95%CI 0.21-0.31), and had less heart affectation (7.6% vs 19%, OR 0.36, 95%CI 0.21-0.62). More proportion of patients without admission had PESI<65 (36% vs 19%, OR 2.45, 95%CI 2.16-2.78). At 7 days, patients treated at home presented less major bleeding (0.1% vs 0.8%, OR 0.11, 95%CI 0.02-0.78), less mortality (0.1% vs 1.6%, OR 0.05, 95%CI 0.01-0.38) and less event composed by recurrent PE, major bleeding and death (0.3% vs 2.4%, OR 0.14, 95%CI 0.05-0.38). Risk factors for the composite event were history of myocardial infarction (HR 1.38, 95%CI 1.01-1.90), chronic heart failure (HR 1.51, 95%CI 1.12-2.04), recent bleeding (HR 2.16, 95%CI 1.35-3.44), active cancer (HR 1.47, 95%CI 1.13-1.92), having transient risk factors (HR 1.67, 95%CI 1.33-2.11) and hospital admission (HR 4.24, 95%CI 1.56-11.57).
Conclusion: PE patients treated at home were younger, less severe and less complicated than patients treated at hospital. Risk factors for the composite event were heart disease, bleeding, cancer and hospital admission.
Footnotes
Cite this article as Eur Respir J 2022; 60: Suppl. 66, 568.
This article was presented at the 2022 ERS International Congress, in session “-”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
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