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Over-the-counter (OTC) short-acting β2-agonist (SABA) purchase and asthma outcomes in SABINA III

H Farouk, W J Mattarucco, R M Barriga, H Wang, D Diaz, A Khattab, M P Gallego, A A Zaabi, D Price
European Respiratory Journal 2022 60: 3434; DOI: 10.1183/13993003.congress-2022.3434
H Farouk
1AstraZeneca, Dubai, Utd.Arab Emir.
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W J Mattarucco
2Neumonólogo, CEPROSS (Centro Profesional San Salvador), Entre Rios, Argentina
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R M Barriga
3Hospital Angeles Chihuahua, Chihuahua, Mexico
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H Wang
4National Taiwan University Hospital, Taipei, Taiwan
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D Diaz
5Lung Center of the Philippines, Manila, Philippines
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A Khattab
6Chest Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
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M P Gallego
7Unversidad Tecnológica de Pereira Y Fundación Universitaria Visión de las Américas. Respiremos S.A.S–Clinical Comfamiliar, Pereira, Colombia
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A A Zaabi
8Zayed Military Hospital, Abu Dhabi, Utd.Arab Emir.
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D Price
9Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom
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Abstract

Background: SABINA III showed that 18% of patients with asthma across 24 countries purchased SABA OTC;1 however, the clinical burden of such unregulated access to SABA is not known.

Objective: To evaluate the clinical characteristics and outcomes of patients with asthma who purchase SABA OTC.

Methods: This post-hoc analysis of SABINA III included patients with asthma aged ≥12 years with SABA prescriptions and/or self-reported OTC SABA purchase (canisters/year).

Results: Of the 8351 patients in SABINA III, 318 had only OTC SABA, 3732 had only SABA prescriptions, and 1101, both prescriptions+OTC SABA (Table 1A). A higher proportion of patients with only OTC SABA vs the other groups were treated in primary care (36.2% vs 19.2% and 14.2%) and had no healthcare reimbursement (47.8% vs 23.8% and 35.5%). Of the 2927 patients prescribed ≥3 SABA canisters, 443 (15.1%) also had ≥3 OTC SABA. These 15.1% had a mean of 2.5 severe exacerbations in the previous year; 78.3% of them had ≥1 severe exacerbation and 65.2% had uncontrolled asthma (Table 1B).

Conclusion: A subset of patients with ≥3 SABA canister prescriptions also purchased ≥3 SABA canisters OTC. These patients had a relatively high disease burden, emphasising the need for regular asthma reviews, for pharmacists to play a key role in monitoring SABA purchase, as well as policy changes to regulate SABA purchase and ensure access to affordable asthma care.

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Footnotes

Cite this article as Eur Respir J 2022; 60: Suppl. 66, 3434.

This article was presented at the 2022 ERS International Congress, in session “-”.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2022
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Over-the-counter (OTC) short-acting β2-agonist (SABA) purchase and asthma outcomes in SABINA III
H Farouk, W J Mattarucco, R M Barriga, H Wang, D Diaz, A Khattab, M P Gallego, A A Zaabi, D Price
European Respiratory Journal Sep 2022, 60 (suppl 66) 3434; DOI: 10.1183/13993003.congress-2022.3434

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Over-the-counter (OTC) short-acting β2-agonist (SABA) purchase and asthma outcomes in SABINA III
H Farouk, W J Mattarucco, R M Barriga, H Wang, D Diaz, A Khattab, M P Gallego, A A Zaabi, D Price
European Respiratory Journal Sep 2022, 60 (suppl 66) 3434; DOI: 10.1183/13993003.congress-2022.3434
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