Table of Contents

01 December 2022; volume 60, issue 6

Editorials

Original Research Articles

  • Interstitial lung disease

    • Nintedanib plus chemotherapy for nonsmall cell lung cancer with idiopathic pulmonary fibrosis: a randomised phase 3 trial
      Kohei Otsubo, Junji Kishimoto, Masahiko Ando, Hirotsugu Kenmotsu, Yuji Minegishi, Hidehito Horinouchi, Terufumi Kato, Eiki Ichihara, Masashi Kondo, Shinji Atagi, Motohiro Tamiya, Satoshi Ikeda, Toshiyuki Harada, Shinnosuke Takemoto, Hidetoshi Hayashi, Keita Nakatomi, Yuichiro Kimura, Yasuhiro Kondoh, Masahiko Kusumoto, Kazuya Ichikado, Nobuyuki Yamamoto, Kazuhiko Nakagawa, Yoichi Nakanishi, Isamu Okamoto
      European Respiratory Journal 60 (6) 2200380; DOI: 10.1183/13993003.00380-2022 Published 15 December 2022

  • Interstitial lung disease and genetics

  • Interstitial lung disease and translational science

  • Lung imaging and interstitial lung disease

  • COPD

    • Open Access
      Detection of COPD in the SUMMIT Study lung cancer screening cohort using symptoms and spirometry
      Sophie Tisi, Jennifer L. Dickson, Carolyn Horst, Samantha L. Quaife, Helen Hall, Priyam Verghese, Kylie Gyertson, Vicky Bowyer, Claire Levermore, Anne-Marie Mullin, Jonathan Teague, Laura Farrelly, Arjun Nair, Anand Devaraj, Allan Hackshaw, the SUMMIT Consortium, John R. Hurst, Sam M. Janes
      European Respiratory Journal 60 (6) 2200795; DOI: 10.1183/13993003.00795-2022 Published 8 December 2022

  • COPD and translational science

    • Adverse roles of mast cell chymase-1 in COPD
      Gang Liu, Andrew G. Jarnicki, Keshav R. Paudel, Wenying Lu, Ridhima Wadhwa, Ashleigh M. Philp, Hannelore Van Eeckhoutte, Jacqueline E. Marshall, Vamshikrishna Malyla, Angelica Katsifis, Michael Fricker, Nicole G. Hansbro, Kamal Dua, Nazanin Z. Kermani, Mathew S. Eapen, Angelica Tiotiu, K. Fan Chung, Gaetano Caramori, Ken Bracke, Ian M. Adcock, Sukhwinder S. Sohal, Peter A. Wark, Brian G. Oliver, Philip M. Hansbro
      European Respiratory Journal 60 (6) 2101431; DOI: 10.1183/13993003.01431-2021 Published 8 December 2022

  • Pulmonary vascular disease

    • Open Access
      An emerging phenotype of pulmonary arterial hypertension patients carrying SOX17 variants
      David Montani, Benoit Lechartier, Barbara Girerd, Mélanie Eyries, Maria-Rosa Ghigna, Laurent Savale, Xavier Jaïs, Andrei Seferian, Mitja Jevnikar, Athénais Boucly, Marianne Riou, Julie Traclet, Ari Chaouat, Maryline Levy, Jerome Le Pavec, Elie Fadel, Frédéric Perros, Florent Soubrier, Martine Remy-Jardin, Olivier Sitbon, Damien Bonnet, Marc Humbert
      European Respiratory Journal 60 (6) 2200656; DOI: 10.1183/13993003.00656-2022 Published 8 December 2022
    • Open Access
      Inhaled seralutinib exhibits potent efficacy in models of pulmonary arterial hypertension
      Anna Galkin, Ravikumar Sitapara, Bryan Clemons, Eduardo Garcia, Michael Kennedy, David Guimond, Laura L. Carter, Ashley Douthitt, Robin Osterhout, Aneta Gandjeva, Deborah Slee, Luisa Salter-Cid, Rubin M. Tuder, Lawrence S. Zisman
      European Respiratory Journal 60 (6) 2102356; DOI: 10.1183/13993003.02356-2021 Published 1 December 2022

  • Pulmonary vascular disease and translational science

  • Respiratory infections

    • Open Access
      A biomarker assay to risk-stratify patients with symptoms of respiratory tract infection
      Shahid Husain, Andrew T. Sage, Lorenzo del Sorbo, Marcelo Cypel, Tereza Martinu, Stephen C. Juvet, Andrea Mariscal, Julie Wright, Bonnie T. Chao, Alaa A. Shamandy, S. Hossein Mousavi, Jin Ma, Bo Wang, Jerome Valero, Mingyao Liu, Megan Landes, Sharaniyaa Balachandran, Kimberley Hudson, Michelle Ngai, Marialessia Capuano, Maria Gelardi, Enrico Lupia, Daniel R. Marinowic, Frederico O. Friedrich, Carine R.R. Schmitz, Leticya S.M. dos Santos, Florencia M. Barbe-Tuana, Marcus H. Jones, Kevin C. Kain, Tony Mazzulli, Sam Sabbah, Shaf Keshavjee
      European Respiratory Journal 60 (6) 2200459; DOI: 10.1183/13993003.00459-2022 Published 15 December 2022

  • COVID-19

    • Open Access
      Immunomodulation and endothelial barrier protection mediate the association between oral imatinib and mortality in hospitalised COVID-19 patients
      Justin de Brabander, Erik Duijvelaar, Job R. Schippers, Patrick J. Smeele, Hessel Peters-Sengers, Jan Willem Duitman, Jurjan Aman, Harm Jan Bogaard, Tom van der Poll, Lieuwe D.J. Bos on behalf of the CounterCOVID Study Group
      European Respiratory Journal 60 (6) 2200780; DOI: 10.1183/13993003.00780-2022 Published 15 December 2022
    • Open Access
      Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages
      Katja Hönzke, Benedikt Obermayer, Christin Mache, Diana Fatykhova, Mirjana Kessler, Simon Dökel, Emanuel Wyler, Morris Baumgardt, Anna Löwa, Karen Hoffmann, Patrick Graff, Jessica Schulze, Maren Mieth, Katharina Hellwig, Zeynep Demir, Barbara Biere, Linda Brunotte, Angeles Mecate-Zambrano, Judith Bushe, Melanie Dohmen, Christian Hinze, Sefer Elezkurtaj, Mario Tönnies, Torsten T. Bauer, Stephan Eggeling, Hong-Linh Tran, Paul Schneider, Jens Neudecker, Jens C. Rückert, Kai M. Schmidt-Ott, Jonas Busch, Frederick Klauschen, David Horst, Helena Radbruch, Josefine Radke, Frank Heppner, Victor M. Corman, Daniela Niemeyer, Marcel A. Müller, Christine Goffinet, Ronja Mothes, Anna Pascual-Reguant, Anja Erika Hauser, Dieter Beule, Markus Landthaler, Stephan Ludwig, Norbert Suttorp, Martin Witzenrath, Achim D. Gruber, Christian Drosten, Leif-Erik Sander, Thorsten Wolff, Stefan Hippenstiel, Andreas C. Hocke
      European Respiratory Journal 60 (6) 2102725; DOI: 10.1183/13993003.02725-2021 Published 1 December 2022

  • Lung function

    • Open Access
      Reference equations for evaluation of spirometry function tests in South Asia, and among South Asians living in other countries
      Wei Yee Leong, Ananya Gupta, Mehedi Hasan, Sara Mahmood, Samreen Siddiqui, Sajjad Ahmed, Ian Y. Goon, Marie Loh, Theresia H. Mina, Benjamin Lam, Yik Weng Yew, Joanne Ngeow, Jimmy Lee, Eng Sing Lee, Elio Riboli, Paul Elliott, Geak Poh Tan, Sanjay H. Chotirmall, Ananda R. Wickremasinghe, Jaspal S. Kooner, Khadija I. Khawaja, Prasad Katulanda, Malay K. Mridha, Sujeet Jha, Anjana Ranjit Mohan, Guha Pradeepa, Anuradhani Kasturiratne, John C. Chambers
      European Respiratory Journal 60 (6) 2102962; DOI: 10.1183/13993003.02962-2021 Published 1 December 2022

  • Asthma

  • Lung cancer

  • Epidemiology

Reviews

State of the Art

  • Towards an artificial human lung: modelling organ-like complexity to aid mechanistic understanding
    Maria Victoria Humbert, Cosma Mirella Spalluto, Joseph Bell, Cornelia Blume, Franco Conforti, Elizabeth R. Davies, Lareb S.N. Dean, Paul Elkington, Hans Michael Haitchi, Claire Jackson, Mark G. Jones, Matthew Loxham, Jane S. Lucas, Hywel Morgan, Marta Polak, Karl J. Staples, Emily J. Swindle, Liku Tezera, Alastair Watson, Tom M.A. Wilkinson
    European Respiratory Journal 60 (6) 2200455; DOI: 10.1183/13993003.00455-2022 Published 8 December 2022

Research letters

Correspondence

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