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The association between immunosuppressants and outcomes of COVID-19

Chi-Kuei Hsu, Chih-Cheng Lai
European Respiratory Journal 2022 60: 2200816; DOI: 10.1183/13993003.00816-2022
Chi-Kuei Hsu
1Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan
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Chih-Cheng Lai
2Department of Internal Medicine, Kaohsiung Veterans General Hospital, Tainan Branch, Tainan, Taiwan
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Extract

We read with great interest the study investigating the association between immunosuppressant and the outcome of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection [1]. They found that the prior use of immunosuppressant would be associated with a significantly increased risk of death (adjusted relative risk (aRR) 1.56, 95% CI 1.10–2.22) which was mainly driven by exposure to systemic glucocorticoids (aRR 2.38, 95% CI 1.72–3.30). Overall, it is a well-designed study; however, we have three concerns about the findings of this study.

Abstract

Immunosuppressants and underlying diseases could affect the outcome of patients of COVID-19, and this requires further analysis https://bit.ly/3A6rSeJ

Footnotes

  • Conflict of interest: C-K. Hsu has nothing to disclose. C-C. Lai has nothing to disclose.

  • Received April 19, 2022.
  • Accepted June 18, 2022.
  • Copyright ©The authors 2022. For reproduction rights and permissions contact permissions{at}ersnet.org
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The association between immunosuppressants and outcomes of COVID-19
Chi-Kuei Hsu, Chih-Cheng Lai
European Respiratory Journal Aug 2022, 60 (2) 2200816; DOI: 10.1183/13993003.00816-2022

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The association between immunosuppressants and outcomes of COVID-19
Chi-Kuei Hsu, Chih-Cheng Lai
European Respiratory Journal Aug 2022, 60 (2) 2200816; DOI: 10.1183/13993003.00816-2022
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