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Diagnosis and treatment of tuberculosis infection: can it contribute to achieving tuberculosis elimination?

Alberto Matteelli, Jan-Willem C. Alffenaar
European Respiratory Journal 2022 60: 2200540; DOI: 10.1183/13993003.00540-2022
Alberto Matteelli
1Institute of Infectious and Tropical diseases, WHO Collaborating Centre for Tuberculosis/HIV coinfection and for the Tuberculosis Elimination Strategy, University of Brescia, Brescia, Italy
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  • For correspondence: alberto.matteelli@unibs.it
Jan-Willem C. Alffenaar
2Sydney Institute for Infectious Diseases, The University of Sydney School of Pharmacy Faculty of Medicine and Health, The University of Sydney, Sydney, Australia
3School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia
4Westmead Hospital, Sydney, Australia
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The END tuberculosis (TB) strategy, launched in 2015, calls for elimination of TB, defined as an incidence of less than one case of the disease per million population [1]. For the first time ever, it broadens the concept of TB control and raises the profile of diagnosis and treatment of the pool of infected individuals from which future TB cases will be generated [2]. Currently, the World Health Organization (WHO) estimates 10 million incident cases per year [3], while the number of persons with the infection is estimated at 1.7 billion [4]. Although not contagious, people with M. tuberculosis infection represent the reservoir for future TB cases. To meet the TB elimination goal, it is imperative that such a reservoir will also be extinguished. Models predict that elimination of TB can be reached by 2050 and that diagnosis and treatment of tuberculosis infection (TBI) outperforms other interventions [5].

Abstract

Management of tuberculosis infection needs to be strengthened to achieve the goal of tuberculosis elimination https://bit.ly/37iYQfD

Footnotes

  • Conflict of interest: The authors have no conflict of interest to be declared.

  • Received March 15, 2022.
  • Accepted April 5, 2022.
  • Copyright ©The authors 2022. For reproduction rights and permissions contact permissions{at}ersnet.org
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Diagnosis and treatment of tuberculosis infection: can it contribute to achieving tuberculosis elimination?
Alberto Matteelli, Jan-Willem C. Alffenaar
European Respiratory Journal Jul 2022, 60 (1) 2200540; DOI: 10.1183/13993003.00540-2022

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Diagnosis and treatment of tuberculosis infection: can it contribute to achieving tuberculosis elimination?
Alberto Matteelli, Jan-Willem C. Alffenaar
European Respiratory Journal Jul 2022, 60 (1) 2200540; DOI: 10.1183/13993003.00540-2022
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