European Respiratory Journal: 59 (5)

01 May 2022; volume 59, issue 5

Editorials

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Sing out for COPD!
Joan B. Soriano, Nicholas S. Hopkinson

European Respiratory Journal 59 (5) 2102961; DOI: 10.1183/13993003.02961-2021 Published 19 May 2022
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The respiratory tract microbiome: moving from correlation to causation
Richard Morton, Aran Singanayagam

European Respiratory Journal 59 (5) 2103079; DOI: 10.1183/13993003.03079-2021 Published 5 May 2022
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Should we rewrite the natural history and prognosis of pulmonary Langerhans cell histiocytosis?
Sergio Harari, Davide Elia

European Respiratory Journal 59 (5) 2200700; DOI: 10.1183/13993003.00700-2022 Published 26 May 2022
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Targeting the nasty nestin to shoot lung fibrosis
Olivier Burgy, Bruno Crestani, Philippe Bonniaud

European Respiratory Journal 59 (5) 2103146; DOI: 10.1183/13993003.03146-2021 Published 5 May 2022
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Quality over quantity: the importance of collecting relevant samples to understand complex diseases
Alen Faiz, Maarten van den Berge

European Respiratory Journal 59 (5) 2200418; DOI: 10.1183/13993003.00418-2022 Published 26 May 2022

ERS Official Documents

ERS statement
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  ERS statement: a core outcome set for clinical trials evaluating the management of COPD exacerbations
  Alexander G. Mathioudakis, Fekri Abroug, Alvar Agusti, Sachin Ananth, Per Bakke, Konstantinos Bartziokas, Bianca Beghe, Andras Bikov, Thomas Bradbury, Guy Brusselle, Cordula Cadus, Courtney Coleman, Marco Contoli, Alexandru Corlateanu, Olga Corlateanu, Gerard J. Criner, Balazs Csoma, Alexander Emelyanov, Rosa Faner, Gustavo Fernandez Romero, Zeineb Hammouda, Peter Horváth, Arturo Huerta Garcia, Michael Jacobs, Christine Jenkins, Guy Joos, Olga Kharevich, Konstantinos Kostikas, Elena Lapteva, Zsofia Lazar, Joerg D. Leuppi, Carol Liddle, John Linnell, Alejandra López-Giraldo, Vanessa M. McDonald, Rune Nielsen, Alberto Papi, Isabel Saraiva, Galina Sergeeva, Agni Sioutkou, Pradeesh Sivapalan, Elizabeth Stovold, Hao Wang, Fuqiang Wen, Janelle Yorke, Paula R. Williamson, Jørgen Vestbo, Jens-Ulrik Jensen on behalf of the DECODE-NET
  
  European Respiratory Journal 59 (5) 2102006; DOI: 10.1183/13993003.02006-2021 Published 5 May 2022

Original Research Articles

COPD
- Open Access
  Use of Singing for Lung Health as an alternative training modality within pulmonary rehabilitation for COPD: a randomised controlled trial
  Mette Kaasgaard, Daniel Bech Rasmussen, Karen Hjerrild Andreasson, Ole Hilberg, Anders Løkke, Peter Vuust, Uffe Bodtger
  
  European Respiratory Journal 59 (5) 2101142; DOI: 10.1183/13993003.01142-2021 Published 19 May 2022
- Open Access
  Whole-body and muscle responses to aerobic exercise training and withdrawal in ageing and COPD
  Lorna E. Latimer, Dumitru Constantin-Teodosiu, Bhavesh Popat, Despina Constantin, Linzy Houchen-Wolloff, Charlotte E. Bolton, Michael C. Steiner, Paul L. Greenhaff
  
  European Respiratory Journal 59 (5) 2101507; DOI: 10.1183/13993003.01507-2021 Published 12 May 2022
Asthma
- Open Access
  Association of blood trihalomethane concentrations with asthma in US adolescents: nationally representative cross-sectional study
  Yang Sun, Peng-Fei Xia, Jing Xie, Vicente Mustieles, Yu Zhang, Yi-Xin Wang, Carmen Messerlian
  
  European Respiratory Journal 59 (5) 2101440; DOI: 10.1183/13993003.01440-2021 Published 26 May 2022
- Open Access
  Short-acting β₂-agonist prescriptions are associated with poor clinical outcomes of asthma: the multi-country, cross-sectional SABINA III study
  Eric D. Bateman, David B. Price, Hao-Chien Wang, Adel Khattab, Patricia Schonffeldt, Angelina Catanzariti, Ralf J.P. van der Valk, Maarten J.H.I. Beekman
  
  European Respiratory Journal 59 (5) 2101402; DOI: 10.1183/13993003.01402-2021 Published 5 May 2022
Paediatrics
- Open Access
  Development of lung diffusion to adulthood following extremely preterm birth
  Emma Satrell, Hege Clemm, Ola Drange Røksund, Karl Ove Hufthammer, Einar Thorsen, Thomas Halvorsen, Maria Vollsæter
  
  European Respiratory Journal 59 (5) 2004103; DOI: 10.1183/13993003.04103-2020 Published 19 May 2022
- Open Access
  Association of early-life factors with prematurity-associated lung disease: prospective cohort study
  Kylie Hart, Michael Cousins, W. John Watkins, Sarah J. Kotecha, A. John Henderson, Sailesh Kotecha
  
  European Respiratory Journal 59 (5) 2101766; DOI: 10.1183/13993003.01766-2021 Published 12 May 2022
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  Violence-related distress and lung function in two longitudinal studies of youth
  Kristina Gaietto, Yueh-Ying Han, Erick Forno, Leonard B. Bacharier, Wanda Phipatanakul, Theresa W. Guilbert, Michael D. Cabana, Kristie Ross, Joshua Blatter, Edna Acosta-Pérez, Gregory E. Miller, Rafael E. de la Hoz, Franziska J. Rosser, Sandy Durrani, Glorisa Canino, Stephen R. Wisniewski, Juan C. Celedón
  
  European Respiratory Journal 59 (5) 2102329; DOI: 10.1183/13993003.02329-2021 Published 12 May 2022
Respiratory infections
- Open Access
  Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
  Charlotte Rigauts, Juliana Aizawa, Steven L. Taylor, Geraint B. Rogers, Matthias Govaerts, Paul Cos, Lisa Ostyn, Sarah Sims, Eva Vandeplassche, Mozes Sze, Yves Dondelinger, Lars Vereecke, Heleen Van Acker, Jodie L. Simpson, Lucy Burr, Anne Willems, Michael M. Tunney, Cristina Cigana, Alessandra Bragonzi, Tom Coenye, Aurélie Crabbé
  
  European Respiratory Journal 59 (5) 2101293; DOI: 10.1183/13993003.01293-2021 Published 5 May 2022
Bronchiectasis
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  Heterogeneity of treatment response in bronchiectasis clinical trials
  Oriol Sibila, Elena Laserna, Amelia Shoemark, Lidia Perea, Diana Bilton, Megan L. Crichton, Anthony De Soyza, Wim G. Boersma, Josje Altenburg, James D. Chalmers
  
  European Respiratory Journal 59 (5) 2100777; DOI: 10.1183/13993003.00777-2021 Published 5 May 2022
Rare lung diseases
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  Long-term outcomes of adult pulmonary Langerhans cell histiocytosis: a prospective cohort
  Amira Benattia, Emmanuelle Bugnet, Anouk Walter-Petrich, Constance de Margerie-Mellon, Véronique Meignin, Agathe Seguin-Givelet, Gwenaël Lorillon, Sylvie Chevret, Abdellatif Tazi
  
  European Respiratory Journal 59 (5) 2101017; DOI: 10.1183/13993003.01017-2021 Published 26 May 2022
Imaging
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  Scan-based competing death risk model for re-evaluating lung cancer computed tomography screening eligibility
  Anton Schreuder, Colin Jacobs, Nikolas Lessmann, Mireille J.M. Broeders, Mario Silva, Ivana Išgum, Pim A. de Jong, Michel M. van den Heuvel, Nicola Sverzellati, Mathias Prokop, Ugo Pastorino, Cornelia M. Schaefer-Prokop, Bram van Ginneken
  
  European Respiratory Journal 59 (5) 2101613; DOI: 10.1183/13993003.01613-2021 Published 12 May 2022
Interstitial lung disease and imaging
- Open Access
  Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis
  Janine Schniering, Malgorzata Maciukiewicz, Hubert S. Gabrys, Matthias Brunner, Christian Blüthgen, Chantal Meier, Sophie Braga-Lagache, Anne-Christine Uldry, Manfred Heller, Matthias Guckenberger, Håvard Fretheim, Christos T. Nakas, Anna-Maria Hoffmann-Vold, Oliver Distler, Thomas Frauenfelder, Stephanie Tanadini-Lang, Britta Maurer
  
  European Respiratory Journal 59 (5) 2004503; DOI: 10.1183/13993003.04503-2020 Published 19 May 2022
Interstitial lung disease and basic science
- Open Access
  Nestin promotes pulmonary fibrosis via facilitating recycling of TGF-β receptor I
  Jiancheng Wang, Xiaofan Lai, Senyu Yao, Hainan Chen, Jianye Cai, Yulong Luo, Yi Wang, Yuan Qiu, Yinong Huang, Xiaoyue Wei, Boyan Wang, Qiying Lu, Yuanjun Guan, Tao Wang, Shiyue Li, Andy Peng Xiang
  
  European Respiratory Journal 59 (5) 2003721; DOI: 10.1183/13993003.03721-2020 Published 5 May 2022
- Open Access
  Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis
  Shengren Song, Zhenli Fu, Ruijuan Guan, Jie Zhao, Penghui Yang, Yang Li, Hang Yin, Yunxin Lai, Gencheng Gong, Simin Zhao, Jiangtian Yu, Xiaomin Peng, Ying He, Yumei Luo, Nanshan Zhong, Jin Su
  
  European Respiratory Journal 59 (5) 2100864; DOI: 10.1183/13993003.00864-2021 Published 5 May 2022
COPD and basic science
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  The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in COPD
  Feng Xu, Dragoş M. Vasilescu, Daisuke Kinose, Naoya Tanabe, Kevin W. Ng, Harvey O. Coxson, Joel D. Cooper, Tillie-Louise Hackett, Stijn E. Verleden, Bart M. Vanaudenaerde, Christopher S. Stevenson, Marc E. Lenburg, Avrum Spira, Wan C. Tan, Don D. Sin, Raymond T. Ng, James C. Hogg
  
  European Respiratory Journal 59 (5) 2101411; DOI: 10.1183/13993003.01411-2021 Published 26 May 2022
Airways disease
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  An interferon-inducible signature of airway disease from blood gene expression profiling
  Jeong H. Yun, Sool Lee, Pooja Srinivasa, Jarrett Morrow, Robert Chase, Aadbida Saferali, Zhonghui Xu, Michael Cho, Peter Castaldi, Craig P. Hersh
  
  European Respiratory Journal 59 (5) 2100569; DOI: 10.1183/13993003.00569-2021 Published 19 May 2022
Lung cancer
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  Guide sheath versus non-guide sheath method for endobronchial ultrasound-guided biopsy of peripheral pulmonary lesions: a multicentre randomised trial
  Masahide Oki, Hideo Saka, Tatsuya Imabayashi, Daisuke Himeji, Yoichi Nishii, Harunori Nakashima, Daisuke Minami, Shotaro Okachi, Yasuyuki Mizumori, Masahiko Ando
  
  European Respiratory Journal 59 (5) 2101678; DOI: 10.1183/13993003.01678-2021 Published 26 May 2022

Review

Open Access
Cardiac sarcoidosis: systematic review of the literature on corticosteroid and immunosuppressive therapies
Julien Stievenart, Guillaume Le Guenno, Marc Ruivard, Virginie Rieu, Marc André, Vincent Grobost

European Respiratory Journal 59 (5) 2100449; DOI: 10.1183/13993003.00449-2021 Published 5 May 2022

Series

Challenges in sleep apnoea
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  Sleep apnoea and heart failure
  Patrick Lévy, Matthew T. Naughton, Renaud Tamisier, Martin R. Cowie, T. Douglas Bradley
  
  European Respiratory Journal 59 (5) 2101640; DOI: 10.1183/13993003.01640-2021 Published 12 May 2022

Agora

Research letters
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  Extended D-dimer cut-offs and machine learning for ruling out pulmonary embolism in individuals undergoing computed tomography pulmonary angiography
  Alessandro N. Franciosi, Nicholas McCarthy, Brian Gaffney, John Duignan, Eamon Sweeney, Niall O'Connell, Karen Murphy, Fionnuala Ní Áinle, Marcus W. Butler, Jonathan D. Dodd, Michael P. Keane, David J. Murphy, Kathleen M. Curran, Cormac McCarthy
  
  European Respiratory Journal 59 (5) 2200075; DOI: 10.1183/13993003.00075-2022 Published 26 May 2022
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  Sputum cell counts in COPD patients who use electronic cigarettes
  Andrew Higham, Augusta Beech, Natalie Jackson, Simon Lea, Dave Singh
  
  European Respiratory Journal 59 (5) 2103016; DOI: 10.1183/13993003.03016-2021 Published 26 May 2022
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  Extracorporeal life support allows lung transplant in anti-MDA5+ rapidly progressive interstitial lung disease
  Pierre Bay, Marc Pineton de Chambrun, Antoine Roux, Vincent Bunel, Alain Combes, Dominique Israël-Biet, Benjamin Zuber, Hilario Nunes, Yves Allenbach, Yurdagül Uzunhan
  
  European Respiratory Journal 59 (5) 2102968; DOI: 10.1183/13993003.02968-2021 Published 26 May 2022
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  Pseudomonas aeruginosa membrane vesicles cause endothelial barrier failure and lung injury
  Mark J. McVey, Mazharul Maishan, Anna Foley, Razan Turki, Elyse J. Roach, Rose Deschler, Sarah Weidenfeld, Neil M. Goldenberg, Cezar M. Khursigara, Wolfgang M. Kuebler
  
  European Respiratory Journal 59 (5) 2101500; DOI: 10.1183/13993003.01500-2021 Published 19 May 2022
- Open Access
  Health risks related to polyurethane foam degradation in CPAP devices used for sleep apnoea treatment
  Andreas Palm, Ludger Grote, Magnus Ekström, Mirjam Ljunggren
  
  European Respiratory Journal 59 (5) 2200237; DOI: 10.1183/13993003.00237-2022 Published 19 May 2022
- Open Access
  Mortality after admission with pneumonia is higher than after admission with an exacerbation of COPD
  Jørgen Vestbo, Grant Waterer, David Leather, Courtney Crim, Nawar Diar Bakerly, Lucy Frith, Loretta Jacques, Catherine Harvey, Imran Satia, Ashley Woodcock on behalf of the Salford Lung Study Investigators
  
  European Respiratory Journal 59 (5) 2102899; DOI: 10.1183/13993003.02899-2021 Published 19 May 2022
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  The identification of prevalent tuberculosis disease through infection screening among high-risk migrants in the Netherlands
  Ineke Spruijt, Chantal Joren, Henrieke Schimmel, Frouke Procee, Yalda Alam, Susan van den Hof, Connie Erkens
  
  European Respiratory Journal 59 (5) 2103018; DOI: 10.1183/13993003.03018-2021 Published 12 May 2022
- Open Access
  Inhaled corticosteroids for outpatients with COVID-19: a meta-analysis
  Todd C. Lee, Émilie Bortolussi-Courval, Sara Belga, Nick Daneman, Adrienne K. Chan, Ryan Hanula, Nicole Ezer, Emily G. McDonald
  
  European Respiratory Journal 59 (5) 2102921; DOI: 10.1183/13993003.02921-2021 Published 5 May 2022
- Open Access
  Aspergillus tracheobronchitis in COVID-19 patients with acute respiratory distress syndrome: a cohort study
  Philipp Koehler, Saskia von Stillfried, Jorge Garcia Borrega, Frieder Fuchs, Jon Salmanton-García, Fabian Pult, Boris Böll, Dennis A. Eichenauer, Alexander Shimabukuro-Vornhagen, Oliver Kurzai, Peter Boor, Matthias Kochanek, Oliver A. Cornely
  
  European Respiratory Journal 59 (5) 2103142; DOI: 10.1183/13993003.03142-2021 Published 5 May 2022
Correspondence
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  Balancing the risks and benefits is essential for reaping the success of adding in-circuit bacterial filters
  Sven Stieglitz, Mohanchandra Mandal, Pradipta Bhakta, Antonio M. Esquinas
  
  European Respiratory Journal 59 (5) 2200562; DOI: 10.1183/13993003.00562-2022 Published 19 May 2022
- Open Access
  Rifapentine access in Europe: growing concerns over key tuberculosis treatment component
  Lorenzo Guglielmetti, Gunar Günther, Claude Leu, Daniela Cirillo, Raquel Duarte, Alberto L. Garcia-Basteiro, Delia Goletti, Mateja Jankovic, Liga Kuksa, Florian P. Maurer, Frédéric Méchaï, Simon Tiberi, Frank van Leth, Nicolas Veziris, Christoph Lange on behalf of the Study Group on Mycobacteria of the European Society of Microbiology and Infectious Diseases (ESGMYC), European Society of Mycobacteriology (ESM), European Respiratory Society (ERS) and, the Tuberculosis Network European Trials group (TBnet)
  
  European Respiratory Journal 59 (5) 2200388; DOI: 10.1183/13993003.00388-2022 Published 19 May 2022
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  Prednisolone plus itraconazole in acute-stage allergic bronchopulmonary aspergillosis complicating asthma: is the benefit worth the risk?
  Alice Havette, Lucile Regard, Nicolas Roche, Pierre-Régis Burgel
  
  European Respiratory Journal 59 (5) 2102924; DOI: 10.1183/13993003.02924-2021 Published 12 May 2022
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  Reply: Prednisolone plus itraconazole in acute-stage allergic bronchopulmonary aspergillosis complicating asthma: is the benefit worth the risk?
  Ritesh Agarwal, Valliappan Muthu
  
  European Respiratory Journal 59 (5) 2102989; DOI: 10.1183/13993003.02989-2021 Published 12 May 2022
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  Methionine supplementation: potential for improving alveolar macrophage function through reverse cholesterol transport?
  Marissa O'Callaghan, Feargal Helly, Elizabeth Tarling, Michael P. Keane, Cormac McCarthy
  
  European Respiratory Journal 59 (5) 2102594; DOI: 10.1183/13993003.02594-2021 Published 5 May 2022
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  Reply: Methionine supplementation: potential for improving alveolar macrophage function through reverse cholesterol transport?
  Alice Hadchouel, Christophe Delacourt
  
  European Respiratory Journal 59 (5) 2102937; DOI: 10.1183/13993003.02937-2021 Published 5 May 2022

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Table of Contents

Editorials

ERS Official Documents

ERS statement

Original Research Articles

COPD

Asthma

Paediatrics

Respiratory infections

Bronchiectasis

Rare lung diseases

Imaging

Interstitial lung disease and imaging

Interstitial lung disease and basic science

COPD and basic science

Airways disease

Lung cancer

Review

Series

Challenges in sleep apnoea

Agora

Research letters

Correspondence

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