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Table of Contents

01 May 2022; volume 59, issue 5

Editorials

  • You have accessRestricted access
    Sing out for COPD!
    Joan B. Soriano, Nicholas S. Hopkinson
    European Respiratory Journal 59 (5) 2102961; DOI: 10.1183/13993003.02961-2021 Published 19 May 2022
  • You have accessRestricted access
    The respiratory tract microbiome: moving from correlation to causation
    Richard Morton, Aran Singanayagam
    European Respiratory Journal 59 (5) 2103079; DOI: 10.1183/13993003.03079-2021 Published 5 May 2022
  • You have accessRestricted access
    Should we rewrite the natural history and prognosis of pulmonary Langerhans cell histiocytosis?
    Sergio Harari, Davide Elia
    European Respiratory Journal 59 (5) 2200700; DOI: 10.1183/13993003.00700-2022 Published 26 May 2022
  • You have accessRestricted access
    Targeting the nasty nestin to shoot lung fibrosis
    Olivier Burgy, Bruno Crestani, Philippe Bonniaud
    European Respiratory Journal 59 (5) 2103146; DOI: 10.1183/13993003.03146-2021 Published 5 May 2022
  • You have accessRestricted access
    Quality over quantity: the importance of collecting relevant samples to understand complex diseases
    Alen Faiz, Maarten van den Berge
    European Respiratory Journal 59 (5) 2200418; DOI: 10.1183/13993003.00418-2022 Published 26 May 2022

ERS Official Documents

  • ERS statement

    • You have accessRestricted access
      ERS statement: a core outcome set for clinical trials evaluating the management of COPD exacerbations
      Alexander G. Mathioudakis, Fekri Abroug, Alvar Agusti, Sachin Ananth, Per Bakke, Konstantinos Bartziokas, Bianca Beghe, Andras Bikov, Thomas Bradbury, Guy Brusselle, Cordula Cadus, Courtney Coleman, Marco Contoli, Alexandru Corlateanu, Olga Corlateanu, Gerard J. Criner, Balazs Csoma, Alexander Emelyanov, Rosa Faner, Gustavo Fernandez Romero, Zeineb Hammouda, Peter Horváth, Arturo Huerta Garcia, Michael Jacobs, Christine Jenkins, Guy Joos, Olga Kharevich, Konstantinos Kostikas, Elena Lapteva, Zsofia Lazar, Joerg D. Leuppi, Carol Liddle, John Linnell, Alejandra López-Giraldo, Vanessa M. McDonald, Rune Nielsen, Alberto Papi, Isabel Saraiva, Galina Sergeeva, Agni Sioutkou, Pradeesh Sivapalan, Elizabeth Stovold, Hao Wang, Fuqiang Wen, Janelle Yorke, Paula R. Williamson, Jørgen Vestbo, Jens-Ulrik Jensen on behalf of the DECODE-NET
      European Respiratory Journal 59 (5) 2102006; DOI: 10.1183/13993003.02006-2021 Published 5 May 2022

Original Research Articles

  • COPD

    • Open Access
      Use of Singing for Lung Health as an alternative training modality within pulmonary rehabilitation for COPD: a randomised controlled trial
      Mette Kaasgaard, Daniel Bech Rasmussen, Karen Hjerrild Andreasson, Ole Hilberg, Anders Løkke, Peter Vuust, Uffe Bodtger
      European Respiratory Journal 59 (5) 2101142; DOI: 10.1183/13993003.01142-2021 Published 19 May 2022
    • Open Access
      Whole-body and muscle responses to aerobic exercise training and withdrawal in ageing and COPD
      Lorna E. Latimer, Dumitru Constantin-Teodosiu, Bhavesh Popat, Despina Constantin, Linzy Houchen-Wolloff, Charlotte E. Bolton, Michael C. Steiner, Paul L. Greenhaff
      European Respiratory Journal 59 (5) 2101507; DOI: 10.1183/13993003.01507-2021 Published 12 May 2022
  • Asthma

    • Open Access
      Association of blood trihalomethane concentrations with asthma in US adolescents: nationally representative cross-sectional study
      Yang Sun, Peng-Fei Xia, Jing Xie, Vicente Mustieles, Yu Zhang, Yi-Xin Wang, Carmen Messerlian
      European Respiratory Journal 59 (5) 2101440; DOI: 10.1183/13993003.01440-2021 Published 26 May 2022
    • Open Access
      Short-acting β2-agonist prescriptions are associated with poor clinical outcomes of asthma: the multi-country, cross-sectional SABINA III study
      Eric D. Bateman, David B. Price, Hao-Chien Wang, Adel Khattab, Patricia Schonffeldt, Angelina Catanzariti, Ralf J.P. van der Valk, Maarten J.H.I. Beekman
      European Respiratory Journal 59 (5) 2101402; DOI: 10.1183/13993003.01402-2021 Published 5 May 2022
  • Paediatrics

    • Open Access
      Development of lung diffusion to adulthood following extremely preterm birth
      Emma Satrell, Hege Clemm, Ola Drange Røksund, Karl Ove Hufthammer, Einar Thorsen, Thomas Halvorsen, Maria Vollsæter
      European Respiratory Journal 59 (5) 2004103; DOI: 10.1183/13993003.04103-2020 Published 19 May 2022
    • Open Access
      Association of early-life factors with prematurity-associated lung disease: prospective cohort study
      Kylie Hart, Michael Cousins, W. John Watkins, Sarah J. Kotecha, A. John Henderson, Sailesh Kotecha
      European Respiratory Journal 59 (5) 2101766; DOI: 10.1183/13993003.01766-2021 Published 12 May 2022
    • You have accessRestricted access
      Violence-related distress and lung function in two longitudinal studies of youth
      Kristina Gaietto, Yueh-Ying Han, Erick Forno, Leonard B. Bacharier, Wanda Phipatanakul, Theresa W. Guilbert, Michael D. Cabana, Kristie Ross, Joshua Blatter, Edna Acosta-Pérez, Gregory E. Miller, Rafael E. de la Hoz, Franziska J. Rosser, Sandy Durrani, Glorisa Canino, Stephen R. Wisniewski, Juan C. Celedón
      European Respiratory Journal 59 (5) 2102329; DOI: 10.1183/13993003.02329-2021 Published 12 May 2022
  • Respiratory infections

    • Open Access
      Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
      Charlotte Rigauts, Juliana Aizawa, Steven L. Taylor, Geraint B. Rogers, Matthias Govaerts, Paul Cos, Lisa Ostyn, Sarah Sims, Eva Vandeplassche, Mozes Sze, Yves Dondelinger, Lars Vereecke, Heleen Van Acker, Jodie L. Simpson, Lucy Burr, Anne Willems, Michael M. Tunney, Cristina Cigana, Alessandra Bragonzi, Tom Coenye, Aurélie Crabbé
      European Respiratory Journal 59 (5) 2101293; DOI: 10.1183/13993003.01293-2021 Published 5 May 2022
  • Bronchiectasis

    • You have accessRestricted access
      Heterogeneity of treatment response in bronchiectasis clinical trials
      Oriol Sibila, Elena Laserna, Amelia Shoemark, Lidia Perea, Diana Bilton, Megan L. Crichton, Anthony De Soyza, Wim G. Boersma, Josje Altenburg, James D. Chalmers
      European Respiratory Journal 59 (5) 2100777; DOI: 10.1183/13993003.00777-2021 Published 5 May 2022
  • Rare lung diseases

    • You have accessRestricted access
      Long-term outcomes of adult pulmonary Langerhans cell histiocytosis: a prospective cohort
      Amira Benattia, Emmanuelle Bugnet, Anouk Walter-Petrich, Constance de Margerie-Mellon, Véronique Meignin, Agathe Seguin-Givelet, Gwenaël Lorillon, Sylvie Chevret, Abdellatif Tazi
      European Respiratory Journal 59 (5) 2101017; DOI: 10.1183/13993003.01017-2021 Published 26 May 2022
  • Imaging

    • You have accessRestricted access
      Scan-based competing death risk model for re-evaluating lung cancer computed tomography screening eligibility
      Anton Schreuder, Colin Jacobs, Nikolas Lessmann, Mireille J.M. Broeders, Mario Silva, Ivana Išgum, Pim A. de Jong, Michel M. van den Heuvel, Nicola Sverzellati, Mathias Prokop, Ugo Pastorino, Cornelia M. Schaefer-Prokop, Bram van Ginneken
      European Respiratory Journal 59 (5) 2101613; DOI: 10.1183/13993003.01613-2021 Published 12 May 2022
  • Interstitial lung disease and imaging

    • Open Access
      Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis
      Janine Schniering, Malgorzata Maciukiewicz, Hubert S. Gabrys, Matthias Brunner, Christian Blüthgen, Chantal Meier, Sophie Braga-Lagache, Anne-Christine Uldry, Manfred Heller, Matthias Guckenberger, Håvard Fretheim, Christos T. Nakas, Anna-Maria Hoffmann-Vold, Oliver Distler, Thomas Frauenfelder, Stephanie Tanadini-Lang, Britta Maurer
      European Respiratory Journal 59 (5) 2004503; DOI: 10.1183/13993003.04503-2020 Published 19 May 2022
  • Interstitial lung disease and basic science

    • Open Access
      Nestin promotes pulmonary fibrosis via facilitating recycling of TGF-β receptor I
      Jiancheng Wang, Xiaofan Lai, Senyu Yao, Hainan Chen, Jianye Cai, Yulong Luo, Yi Wang, Yuan Qiu, Yinong Huang, Xiaoyue Wei, Boyan Wang, Qiying Lu, Yuanjun Guan, Tao Wang, Shiyue Li, Andy Peng Xiang
      European Respiratory Journal 59 (5) 2003721; DOI: 10.1183/13993003.03721-2020 Published 5 May 2022
    • Open Access
      Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis
      Shengren Song, Zhenli Fu, Ruijuan Guan, Jie Zhao, Penghui Yang, Yang Li, Hang Yin, Yunxin Lai, Gencheng Gong, Simin Zhao, Jiangtian Yu, Xiaomin Peng, Ying He, Yumei Luo, Nanshan Zhong, Jin Su
      European Respiratory Journal 59 (5) 2100864; DOI: 10.1183/13993003.00864-2021 Published 5 May 2022
  • COPD and basic science

    • You have accessRestricted access
      The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in COPD
      Feng Xu, Dragoş M. Vasilescu, Daisuke Kinose, Naoya Tanabe, Kevin W. Ng, Harvey O. Coxson, Joel D. Cooper, Tillie-Louise Hackett, Stijn E. Verleden, Bart M. Vanaudenaerde, Christopher S. Stevenson, Marc E. Lenburg, Avrum Spira, Wan C. Tan, Don D. Sin, Raymond T. Ng, James C. Hogg
      European Respiratory Journal 59 (5) 2101411; DOI: 10.1183/13993003.01411-2021 Published 26 May 2022
  • Airways disease

    • You have accessRestricted access
      An interferon-inducible signature of airway disease from blood gene expression profiling
      Jeong H. Yun, Sool Lee, Pooja Srinivasa, Jarrett Morrow, Robert Chase, Aadbida Saferali, Zhonghui Xu, Michael Cho, Peter Castaldi, Craig P. Hersh
      European Respiratory Journal 59 (5) 2100569; DOI: 10.1183/13993003.00569-2021 Published 19 May 2022
  • Lung cancer

    • You have accessRestricted access
      Guide sheath versus non-guide sheath method for endobronchial ultrasound-guided biopsy of peripheral pulmonary lesions: a multicentre randomised trial
      Masahide Oki, Hideo Saka, Tatsuya Imabayashi, Daisuke Himeji, Yoichi Nishii, Harunori Nakashima, Daisuke Minami, Shotaro Okachi, Yasuyuki Mizumori, Masahiko Ando
      European Respiratory Journal 59 (5) 2101678; DOI: 10.1183/13993003.01678-2021 Published 26 May 2022

Review

  • Open Access
    Cardiac sarcoidosis: systematic review of the literature on corticosteroid and immunosuppressive therapies
    Julien Stievenart, Guillaume Le Guenno, Marc Ruivard, Virginie Rieu, Marc André, Vincent Grobost
    European Respiratory Journal 59 (5) 2100449; DOI: 10.1183/13993003.00449-2021 Published 5 May 2022

Series

  • Challenges in sleep apnoea

    • You have accessRestricted access
      Sleep apnoea and heart failure
      Patrick Lévy, Matthew T. Naughton, Renaud Tamisier, Martin R. Cowie, T. Douglas Bradley
      European Respiratory Journal 59 (5) 2101640; DOI: 10.1183/13993003.01640-2021 Published 12 May 2022

Agora

  • Research letters

    • You have accessRestricted access
      Extended D-dimer cut-offs and machine learning for ruling out pulmonary embolism in individuals undergoing computed tomography pulmonary angiography
      Alessandro N. Franciosi, Nicholas McCarthy, Brian Gaffney, John Duignan, Eamon Sweeney, Niall O'Connell, Karen Murphy, Fionnuala Ní Áinle, Marcus W. Butler, Jonathan D. Dodd, Michael P. Keane, David J. Murphy, Kathleen M. Curran, Cormac McCarthy
      European Respiratory Journal 59 (5) 2200075; DOI: 10.1183/13993003.00075-2022 Published 26 May 2022
    • You have accessRestricted access
      Sputum cell counts in COPD patients who use electronic cigarettes
      Andrew Higham, Augusta Beech, Natalie Jackson, Simon Lea, Dave Singh
      European Respiratory Journal 59 (5) 2103016; DOI: 10.1183/13993003.03016-2021 Published 26 May 2022
    • You have accessRestricted access
      Extracorporeal life support allows lung transplant in anti-MDA5+ rapidly progressive interstitial lung disease
      Pierre Bay, Marc Pineton de Chambrun, Antoine Roux, Vincent Bunel, Alain Combes, Dominique Israël-Biet, Benjamin Zuber, Hilario Nunes, Yves Allenbach, Yurdagül Uzunhan
      European Respiratory Journal 59 (5) 2102968; DOI: 10.1183/13993003.02968-2021 Published 26 May 2022
    • You have accessRestricted access
      Pseudomonas aeruginosa membrane vesicles cause endothelial barrier failure and lung injury
      Mark J. McVey, Mazharul Maishan, Anna Foley, Razan Turki, Elyse J. Roach, Rose Deschler, Sarah Weidenfeld, Neil M. Goldenberg, Cezar M. Khursigara, Wolfgang M. Kuebler
      European Respiratory Journal 59 (5) 2101500; DOI: 10.1183/13993003.01500-2021 Published 19 May 2022
    • Open Access
      Health risks related to polyurethane foam degradation in CPAP devices used for sleep apnoea treatment
      Andreas Palm, Ludger Grote, Magnus Ekström, Mirjam Ljunggren
      European Respiratory Journal 59 (5) 2200237; DOI: 10.1183/13993003.00237-2022 Published 19 May 2022
    • Open Access
      Mortality after admission with pneumonia is higher than after admission with an exacerbation of COPD
      Jørgen Vestbo, Grant Waterer, David Leather, Courtney Crim, Nawar Diar Bakerly, Lucy Frith, Loretta Jacques, Catherine Harvey, Imran Satia, Ashley Woodcock on behalf of the Salford Lung Study Investigators
      European Respiratory Journal 59 (5) 2102899; DOI: 10.1183/13993003.02899-2021 Published 19 May 2022
    • You have accessRestricted access
      The identification of prevalent tuberculosis disease through infection screening among high-risk migrants in the Netherlands
      Ineke Spruijt, Chantal Joren, Henrieke Schimmel, Frouke Procee, Yalda Alam, Susan van den Hof, Connie Erkens
      European Respiratory Journal 59 (5) 2103018; DOI: 10.1183/13993003.03018-2021 Published 12 May 2022
    • Open Access
      Inhaled corticosteroids for outpatients with COVID-19: a meta-analysis
      Todd C. Lee, Émilie Bortolussi-Courval, Sara Belga, Nick Daneman, Adrienne K. Chan, Ryan Hanula, Nicole Ezer, Emily G. McDonald
      European Respiratory Journal 59 (5) 2102921; DOI: 10.1183/13993003.02921-2021 Published 5 May 2022
    • Open Access
      Aspergillus tracheobronchitis in COVID-19 patients with acute respiratory distress syndrome: a cohort study
      Philipp Koehler, Saskia von Stillfried, Jorge Garcia Borrega, Frieder Fuchs, Jon Salmanton-García, Fabian Pult, Boris Böll, Dennis A. Eichenauer, Alexander Shimabukuro-Vornhagen, Oliver Kurzai, Peter Boor, Matthias Kochanek, Oliver A. Cornely
      European Respiratory Journal 59 (5) 2103142; DOI: 10.1183/13993003.03142-2021 Published 5 May 2022
  • Correspondence

    • You have accessRestricted access
      Balancing the risks and benefits is essential for reaping the success of adding in-circuit bacterial filters
      Sven Stieglitz, Mohanchandra Mandal, Pradipta Bhakta, Antonio M. Esquinas
      European Respiratory Journal 59 (5) 2200562; DOI: 10.1183/13993003.00562-2022 Published 19 May 2022
    • You have accessRestricted access
      Rifapentine access in Europe: growing concerns over key tuberculosis treatment component
      Lorenzo Guglielmetti, Gunar Günther, Claude Leu, Daniela Cirillo, Raquel Duarte, Alberto L. Garcia-Basteiro, Delia Goletti, Mateja Jankovic, Liga Kuksa, Florian P. Maurer, Frédéric Méchaï, Simon Tiberi, Frank van Leth, Nicolas Veziris, Christoph Lange on behalf of the Study Group on Mycobacteria of the European Society of Microbiology and Infectious Diseases (ESGMYC), European Society of Mycobacteriology (ESM), European Respiratory Society (ERS) and, the Tuberculosis Network European Trials group (TBnet)
      European Respiratory Journal 59 (5) 2200388; DOI: 10.1183/13993003.00388-2022 Published 19 May 2022
    • You have accessRestricted access
      Prednisolone plus itraconazole in acute-stage allergic bronchopulmonary aspergillosis complicating asthma: is the benefit worth the risk?
      Alice Havette, Lucile Regard, Nicolas Roche, Pierre-Régis Burgel
      European Respiratory Journal 59 (5) 2102924; DOI: 10.1183/13993003.02924-2021 Published 12 May 2022
    • You have accessRestricted access
      Reply: Prednisolone plus itraconazole in acute-stage allergic bronchopulmonary aspergillosis complicating asthma: is the benefit worth the risk?
      Ritesh Agarwal, Valliappan Muthu
      European Respiratory Journal 59 (5) 2102989; DOI: 10.1183/13993003.02989-2021 Published 12 May 2022
    • You have accessRestricted access
      Methionine supplementation: potential for improving alveolar macrophage function through reverse cholesterol transport?
      Marissa O'Callaghan, Feargal Helly, Elizabeth Tarling, Michael P. Keane, Cormac McCarthy
      European Respiratory Journal 59 (5) 2102594; DOI: 10.1183/13993003.02594-2021 Published 5 May 2022
    • You have accessRestricted access
      Reply: Methionine supplementation: potential for improving alveolar macrophage function through reverse cholesterol transport?
      Alice Hadchouel, Christophe Delacourt
      European Respiratory Journal 59 (5) 2102937; DOI: 10.1183/13993003.02937-2021 Published 5 May 2022
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European Respiratory Journal: 59 (5)
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