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CPAnet: the challenges of gaining evidence-based knowledge in chronic pulmonary aspergillosis

Rosanne Sprute, Helmut J.F. Salzer, Danila Seidel
European Respiratory Journal 2022 59: 2102879; DOI: 10.1183/13993003.02879-2021
Rosanne Sprute
1Dept of Internal Medicine, Faculty of Medicine and University of Cologne, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany
2Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany
3German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany
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  • For correspondence: rosanne.sprute@uk-koeln.de
Helmut J.F. Salzer
4Dept of Internal Medicine/Pulmonology, Kepler University Hospital, Linz, Austria
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Danila Seidel
1Dept of Internal Medicine, Faculty of Medicine and University of Cologne, Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany
2Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany
3German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany
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Extract

The term chronic pulmonary aspergillosis (CPA) is used to describe a wide range of severe chronic fungal infections mainly occurring in non-immunocompromised patients with pre-existing lung disease [1]. CPA is a long-term infection of the lung caused by moulds of the genus Aspergillus. In Europe, the majority of cases are caused by A. fumigatus. About three million people are diagnosed with CPA globally, mostly complicating tuberculosis, allergic bronchopulmonary aspergillosis (ABPA) or sarcoidosis [2].

Abstract

Chronic pulmonary aspergillosis is a destructive fungal disease complicating many respiratory disorders. Evidence is scarce for clinical management decisions. CPAnet aims to improve patient care by collecting data in an international registry. https://bit.ly/3utUFH1

Acknowledgements

This article was written on behalf of all CPAnet members. We thank the ERS for being selected as an ERS Clinical Research Collaboration.

Footnotes

  • Author contributions: All authors contributed equally.

  • Conflict of interest: All authors have nothing to disclose.

  • Received November 7, 2021.
  • Accepted February 1, 2022.
  • Copyright ©The authors 2022. For reproduction rights and permissions contact permissions{at}ersnet.org
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CPAnet: the challenges of gaining evidence-based knowledge in chronic pulmonary aspergillosis
Rosanne Sprute, Helmut J.F. Salzer, Danila Seidel
European Respiratory Journal Apr 2022, 59 (4) 2102879; DOI: 10.1183/13993003.02879-2021

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CPAnet: the challenges of gaining evidence-based knowledge in chronic pulmonary aspergillosis
Rosanne Sprute, Helmut J.F. Salzer, Danila Seidel
European Respiratory Journal Apr 2022, 59 (4) 2102879; DOI: 10.1183/13993003.02879-2021
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