Extract
We read with great interest the paper by Dickens et al. [1] entitled “Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant” recently published in the European Respiratory Journal.
Abstract
The manuscript by Dickens and co-workers examines biosynthesis of surfactant protein C (SP-C). However, limitations in the model system used and bioproperties of SP-C necessitate further studies to support many of the stated conclusions. https://bit.ly/3ACTRRl
Footnotes
Conflict of interest: M.F. Beers reports grants from National Institutes of Health U01 HL152970, United States Department of Veterans Affairs, Bristol Meyers Squibb, Inc. and Optikira, LLC; license (SftpcI73T mouse) payments to institution from Galapagos, Inc., license (SftpcC121G mouse) payments to both from BMS-Celgene; consulting fees from Boehringer Ingelheim and Gilead Sciences, Inc.; outside the submitted work. All other authors have nothing to disclose.
Support statement: Funding was received from VA Merit Review 1I01BX001176, NIH RO1 HL119436, NIH U01 HL152970 and the Pulmonary Fibrosis Foundation (all to M.F. Beers). Funding information for this article has been deposited with the Crossref Funder Registry.
- Received November 24, 2021.
- Accepted January 20, 2022.
- Copyright ©The authors 2022. For reproduction rights and permissions contact permissions{at}ersnet.org
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