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Table of Contents

01 March 2022; volume 59, issue 3

Editorials

  • You have accessRestricted access
    Commemorating World Tuberculosis Day 2022: recent ERJ articles of critical relevance to ending TB and saving lives
    Giovanni Battista Migliori, Dennis Falzon, Guy B. Marks, Delia Goletti, Tereza Kasaeva, Susanna Esposito, Marc Humbert
    European Respiratory Journal 59 (3) 2200149; DOI: 10.1183/13993003.00149-2022 Published 24 March 2022
  • You have accessRestricted access
    Air pollution susceptibility in children with asthma and obesity: tidal volume as key player?
    Judith M. Vonk, Jolt Roukema
    European Respiratory Journal 59 (3) 2102505; DOI: 10.1183/13993003.02505-2021 Published 3 March 2022
  • You have accessRestricted access
    Adaptive immune responses and protein homeostasis in COPD: the immunoproteasome
    Francesca Polverino
    European Respiratory Journal 59 (3) 2102557; DOI: 10.1183/13993003.02557-2021 Published 3 March 2022
  • You have accessRestricted access
    Systematic reviews and meta-analyses in animal model research: as necessary, and with similar pros and cons, as in patient research
    Ramon Farré, Miguel A. Martínez-García, David Gozal
    European Respiratory Journal 59 (3) 2102438; DOI: 10.1183/13993003.02438-2021 Published 17 March 2022

Original Research Articles

  • Tuberculosis

    • Open Access
      Tuberculosis and COVID-19 co-infection: description of the global cohort
      The TB/COVID-19 Global Study Group
      European Respiratory Journal 59 (3) 2102538; DOI: 10.1183/13993003.02538-2021 Published 24 March 2022
    • Open Access
      Emergence of bedaquiline resistance in a high tuberculosis burden country
      Elena Chesov, Dumitru Chesov, Florian P. Maurer, Sönke Andres, Christian Utpatel, Ivan Barilar, Ana Donica, Maja Reimann, Stefan Niemann, Christoph Lange, Valeriu Crudu, Jan Heyckendorf, Matthias Merker
      European Respiratory Journal 59 (3) 2100621; DOI: 10.1183/13993003.00621-2021 Published 24 March 2022
    • Open Access
      Drug exposure and susceptibility of second-line drugs correlate with treatment response in patients with multidrug-resistant tuberculosis: a multicentre prospective cohort study in China
      Xubin Zheng, Lina Davies Forsman, Ziwei Bao, Yan Xie, Zhu Ning, Thomas Schön, Judith Bruchfeld, Biao Xu, Jan-Willem Alffenaar, Yi Hu
      European Respiratory Journal 59 (3) 2101925; DOI: 10.1183/13993003.01925-2021 Published 24 March 2022
  • Interstitial lung disease

    • You have accessRestricted access
      Biomarker signatures for progressive idiopathic pulmonary fibrosis
      Britt Clynick, Tamera J. Corte, Helen E. Jo, Iain Stewart, Ian N. Glaspole, Christopher Grainge, Toby M. Maher, Vidya Navaratnam, Richard Hubbard, Peter M.A. Hopkins, Paul N. Reynolds, Sally Chapman, Christopher Zappala, Gregory J. Keir, Wendy A. Cooper, Annabelle M. Mahar, Samantha Ellis, Nicole S. Goh, Emma De Jong, Lilian Cha, Dino B.A. Tan, Lucy Leigh, Christopher Oldmeadow, E. Haydn Walters, R. Gisli Jenkins, Yuben Moodley
      European Respiratory Journal 59 (3) 2101181; DOI: 10.1183/13993003.01181-2021 Published 31 March 2022
    • Open Access
      Nintedanib in progressive interstitial lung diseases: data from the whole INBUILD trial
      Kevin R. Flaherty, Athol U. Wells, Vincent Cottin, Anand Devaraj, Yoshikazu Inoue, Luca Richeldi, Simon L.F. Walsh, Martin Kolb, Dirk Koschel, Teng Moua, Susanne Stowasser, Rainer-Georg Goeldner, Rozsa Schlenker-Herceg, Kevin K. Brown on behalf of the INBUILD Trial Investigators
      European Respiratory Journal 59 (3) 2004538; DOI: 10.1183/13993003.04538-2020 Published 17 March 2022
  • Acute lung injury and critical care

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      Helmet noninvasive ventilation compared to facemask noninvasive ventilation and high-flow nasal cannula in acute respiratory failure: a systematic review and meta-analysis
      Dipayan Chaudhuri, Rehman Jinah, Karen E.A. Burns, Federico Angriman, Bruno L. Ferreyro, Laveena Munshi, Ewan Goligher, Damon Scales, Deborah J. Cook, Tommaso Mauri, Bram Rochwerg
      European Respiratory Journal 59 (3) 2101269; DOI: 10.1183/13993003.01269-2021 Published 10 March 2022
  • Pulmonary hypertension and genetics

    • Open Access
      Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension
      Mark Toshner, Colin Church, Lars Harbaum, Christopher Rhodes, Sofia S. Villar Moreschi, James Liley, Rowena Jones, Amit Arora, Ken Batai, Ankit A. Desai, John G. Coghlan, J. Simon R. Gibbs, Dee Gor, Stefan Gräf, Louise Harlow, Jules Hernandez-Sanchez, Luke S. Howard, Marc Humbert, Jason Karnes, David G. Kiely, Rick Kittles, Emily Knightbridge, Brian Lam, Katie A. Lutz, William C. Nichols, Michael W. Pauciulo, Joanna Pepke-Zaba, Jay Suntharalingam, Florent Soubrier, Richard C. Trembath, Tae-Hwi L. Schwantes-An, S. John Wort, Martin R. Wilkins, Sean Gaine, Nicholas W. Morrell, Paul A. Corris the Uniphy Clinical Trials Network
      European Respiratory Journal 59 (3) 2002463; DOI: 10.1183/13993003.02463-2020 Published 10 March 2022
  • Lung cancer

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      Relationship between glucosamine use and the risk of lung cancer: data from a nationwide prospective cohort study
      Guowei Li, Xuhui Zhang, Yingxin Liu, Junguo Zhang, Likang Li, Xin Huang, Lehana Thabane, Gregory Y.H. Lip
      European Respiratory Journal 59 (3) 2101399; DOI: 10.1183/13993003.01399-2021 Published 10 March 2022
  • Cystic fibrosis

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      Association of lung clearance index with survival in individuals with cystic fibrosis
      Johanna Manuela Kurz, Kathryn Angela Ramsey, Romy Rodriguez, Ben Spycher, Reta Fischer Biner, Philipp Latzin, Florian Singer
      European Respiratory Journal 59 (3) 2100432; DOI: 10.1183/13993003.00432-2021 Published 3 March 2022
  • Cystic fibrosis and imaging

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      Artificial intelligence in computed tomography for quantifying lung changes in the era of CFTR modulators
      Gael Dournes, Chase S. Hall, Matthew M. Willmering, Alan S. Brody, Julie Macey, Stephanie Bui, Baudouin Denis de Senneville, Patrick Berger, François Laurent, Ilyes Benlala, Jason C. Woods
      European Respiratory Journal 59 (3) 2100844; DOI: 10.1183/13993003.00844-2021 Published 3 March 2022
  • Asthma

    • You have accessRestricted access
      Identification of asthma-associated microRNAs in bronchial biopsies
      Mirjam P. Roffel, Ilse M. Boudewijn, Jos L.L. van Nijnatten, Alen Faiz, Corneel J. Vermeulen, Antoon J. van Oosterhout, Karen Affleck, Wim Timens, Ken R. Bracke, Tania Maes, Irene H. Heijink, Corry-Anke Brandsma, Maarten van den Berge
      European Respiratory Journal 59 (3) 2101294; DOI: 10.1183/13993003.01294-2021 Published 17 March 2022
    • You have accessRestricted access
      Anti-IL5 mepolizumab minimally influences residual blood eosinophils in severe asthma
      Glenn Van Hulst, Joseph Jorssen, Nathalie Jacobs, Monique Henket, Renaud Louis, Florence Schleich, Fabrice Bureau, Christophe J. Desmet
      European Respiratory Journal 59 (3) 2100935; DOI: 10.1183/13993003.00935-2021 Published 17 March 2022
    • Open Access
      Novel mechanisms of action contributing to benralizumab's potent anti-eosinophilic activity
      Rania Dagher, Varsha Kumar, Alan M. Copenhaver, Sandra Gallagher, Mahboobe Ghaedi, Jonathan Boyd, Paul Newbold, Alison A. Humbles, Roland Kolbeck
      European Respiratory Journal 59 (3) 2004306; DOI: 10.1183/13993003.04306-2020 Published 3 March 2022
  • Asthma and paediatrics

    • You have accessRestricted access
      Obesity, tidal volume, and pulmonary deposition of fine particulate matter in children with asthma
      Nima Afshar-Mohajer, Tianshi David Wu, Rebecca Shade, Emily Brigham, Han Woo, Megan Wood, Rachelle Koehl, Kirsten Koehler, Jason Kirkness, Nadia N. Hansel, Gurumurthy Ramchandran, Meredith C. McCormack
      European Respiratory Journal 59 (3) 2100209; DOI: 10.1183/13993003.00209-2021 Published 3 March 2022
  • Asthma and infection

    • Open Access
      Asthma and COVID-19 risk: a systematic review and meta-analysis
      Anthony P. Sunjaya, Sabine M. Allida, Gian Luca Di Tanna, Christine R. Jenkins
      European Respiratory Journal 59 (3) 2101209; DOI: 10.1183/13993003.01209-2021 Published 31 March 2022
  • Infection

    • You have accessRestricted access
      Lifting dyspnoea invisibility: COVID-19 face masks, the experience of breathing discomfort, and improved lung health perception – a French nationwide survey
      Laure Serresse, Noémie Simon-Tillaux, Maxens Decavèle, Frederick Gay, Nathalie Nion, Sophie Lavault, Antoine Guerder, Antoine Châtelet, Frédéric Dabi, Alexandre Demoule, Capucine Morélot-Panzini, Caroline Moricot, Thomas Similowski
      European Respiratory Journal 59 (3) 2101459; DOI: 10.1183/13993003.01459-2021 Published 31 March 2022
    • You have accessRestricted access
      Blood leukocyte transcriptomes in Gram-positive and Gram-negative community-acquired pneumonia
      Liza Pereverzeva, Fabrice Uhel, Hessel Peters Sengers, Joe Butler, Lonneke A. van Vught, Katie L. Burnham, Emma E. Davenport, Julian C. Knight, Olaf L. Cremer, Marcus J. Schultz, Marc M.J. Bonten, Brendon P. Scicluna, Tom van der Poll on behalf of the MARS consortium
      European Respiratory Journal 59 (3) 2101856; DOI: 10.1183/13993003.01856-2021 Published 17 March 2022
    • You have accessRestricted access
      In-hospital and midterm post-discharge complications of adults hospitalised with respiratory syncytial virus infection in France, 2017–2019: an observational study
      Alexandre Descamps, Nezha Lenzi, Florence Galtier, Fabrice Lainé, Zineb Lesieur, Philippe Vanhems, Sélilah Amour, Anne-Sophie L'Honneur, Nadhira Fidouh, Vincent Foulongne, Gisèle Lagathu, Xavier Duval, Corinne Merle, Bruno Lina, Fabrice Carrat, Odile Launay, Paul Loubet on behalf of the FLUVAC study group
      European Respiratory Journal 59 (3) 2100651; DOI: 10.1183/13993003.00651-2021 Published 3 March 2022
  • Lung cancer and basic science

    • Open Access
      Lrig1 expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth
      Laura Succony, Sandra Gómez-López, Adam Pennycuick, Ahmed S.N. Alhendi, Derek Davies, Sarah E. Clarke, Kate H.C. Gowers, Nicholas A. Wright, Kim B. Jensen, Sam M. Janes
      European Respiratory Journal 59 (3) 2000816; DOI: 10.1183/13993003.00816-2020 Published 31 March 2022
  • COPD and basic science

    • Open Access
      Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy
      Ilona E. Kammerl, Sophie Hardy, Claudia Flexeder, Andrea Urmann, Julia Peierl, Yuqin Wang, Oliver Vosyka, Marion Frankenberger, Katrin Milger, Jürgen Behr, Andrea Koch, Juliane Merl-Pham, Stefanie M. Hauck, Charles Pilette, Holger Schulz, Silke Meiners
      European Respiratory Journal 59 (3) 2101798; DOI: 10.1183/13993003.01798-2021 Published 3 March 2022

Review

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    Intermittent hypoxia-related alterations in vascular structure and function: a systematic review and meta-analysis of rodent data
    Olfa Harki, Quentin Boete, Jean-Louis Pépin, Claire Arnaud, Elise Belaidi, Gilles Faury, Charles Khouri, Anne Briançon-Marjollet
    European Respiratory Journal 59 (3) 2100866; DOI: 10.1183/13993003.00866-2021 Published 17 March 2022

Agora

  • Research letters

    • Open Access
      Bedaquiline can act as core drug in a standardised treatment regimen for fluoroquinolone-resistant rifampicin-resistant tuberculosis
      Tom Decroo, Kya Jai Maug Aung, Mohamed Anwar Hossain, Mourad Gumusboga, Nimer Ortuno-Gutierrez, Bouke Catherine De Jong, Armand Van Deun
      European Respiratory Journal 59 (3) 2102124; DOI: 10.1183/13993003.02124-2021 Published 24 March 2022
    • You have accessRestricted access
      Tailored approaches facilitate high completion of tuberculosis infection treatment among migrants
      Ineke Spruijt, Chantal Joren, Susan van den Hof, Connie Erkens
      European Respiratory Journal 59 (3) 2102077; DOI: 10.1183/13993003.02077-2021 Published 24 March 2022
    • Open Access
      QIAreach QuantiFERON-TB for the diagnosis of Mycobacterium tuberculosis infection
      Francesca Saluzzo, Paola Mantegani, Valeria Poletti de Chaurand, Daniela Maria Cirillo
      European Respiratory Journal 59 (3) 2102563; DOI: 10.1183/13993003.02563-2021 Published 24 March 2022
    • Open Access
      In vivo microevolution of Mycobacterium tuberculosis and transient emergence of atpE_Ala63Pro mutation during treatment in a pre-XDR TB patient
      Arash Ghodousi, Alamdar Hussain Rizvi, Faisal Masood Khanzada, Nasim Akhtar, Abdul Ghafoor, Alberto Trovato, Daniela Maria Cirillo, Sabira Tahseen
      European Respiratory Journal 59 (3) 2102102; DOI: 10.1183/13993003.02102-2021 Published 24 March 2022
    • Open Access
      Cycloserine did not increase depression incidence or severity at standard dosing for multidrug-resistant tuberculosis
      Jeffrey A. Tornheim, Zarir F. Udwadia, Prerna R. Arora, Ishita Gajjar, Nikhil Gupte, Samridhi Sharma, Megha Karane, Namrata Sawant, Nisha Kharat, Alexander J. Blum, Shri Vijay Bala Yogendra Shivakumar, Jai B. Mullerpattan, Lancelot M. Pinto, Tester F. Ashavaid, Amita Gupta, Camilla Rodrigues
      European Respiratory Journal 59 (3) 2102511; DOI: 10.1183/13993003.02511-2021 Published 24 March 2022
    • Open Access
      Global reporting on tuberculosis preventive treatment among contacts
      Dennis Falzon, Saskia den Boon, Avinash Kanchar, Matteo Zignol, Giovanni Battista Migliori, Tereza Kasaeva
      European Respiratory Journal 59 (3) 2102753; DOI: 10.1183/13993003.02753-2021 Published 24 March 2022
    • Open Access
      Acute exacerbation of idiopathic pulmonary fibrosis after SARS-CoV-2 vaccination
      Tomohiro Bando, Reoto Takei, Yoshikazu Mutoh, Hajime Sasano, Yasuhiko Yamano, Toshiki Yokoyama, Toshiaki Matsuda, Kensuke Kataoka, Tomoki Kimura, Yasuhiro Kondoh
      European Respiratory Journal 59 (3) 2102806; DOI: 10.1183/13993003.02806-2021 Published 10 March 2022
    • Open Access
      Add-on inhaled budesonide in the treatment of hospitalised patients with COVID-19: a randomised clinical trial
      Alvar Agustí, Gaston De Stefano, Alberto Levi, Xavier Muñoz, Christian Romero-Mesones, Oriol Sibila, Alejandra Lopez-Giraldo, Vicente Plaza Moral, Elena Curto, Andrés L. Echazarreta, Silvana E. Márquez, Sergi Pascual-Guàrdia, Salud Santos, Alicia Marin, Luis Valdés, Fernando Saldarini, Clara Salgado, Georgina Casanovas, Sara Varea, José Ríos, Rosa Faner
      European Respiratory Journal 59 (3) 2103036; DOI: 10.1183/13993003.03036-2021 Published 10 March 2022
    • You have accessRestricted access
      Gender and racial equity in clinical research for idiopathic pulmonary fibrosis: a systematic review and meta-analysis
      Annie-Claude Jalbert, Lyna Siafa, Agnihotram V. Ramanakumar, Deborah Assayag
      European Respiratory Journal 59 (3) 2102969; DOI: 10.1183/13993003.02969-2021 Published 3 March 2022
    • Open Access
      Lung function during and after acute respiratory infection in COVID-19 positive and negative outpatients
      Pekka Tamminen, Dominik Kerimov, Hanna Viskari, Janne Aittoniemi, Jaana Syrjänen, Lauri Lehtimäki
      European Respiratory Journal 59 (3) 2102837; DOI: 10.1183/13993003.02837-2021 Published 3 March 2022
  • Correspondence

    • You have accessRestricted access
      Methodological caveats regarding “Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant”
      Surafel Mulugeta, Timothy E. Weaver, Michael F. Beers
      European Respiratory Journal 59 (3) 2102974; DOI: 10.1183/13993003.02974-2021 Published 31 March 2022
    • You have accessRestricted access
      The coexistence of asthma and COPD: some considerations about prevalence and lung function decline
      Alessandro Marcon, Francesca Locatelli, Simone Accordini
      European Respiratory Journal 59 (3) 2200096; DOI: 10.1183/13993003.00096-2022 Published 17 March 2022
    • Open Access
      Measurement of hypoxia in the lung in idiopathic pulmonary fibrosis: a matter of control
      Pierre-Simon Bellaye, Guillaume Beltramo, Olivier Burgy, Bertrand Collin, Alexandre Cochet, Philippe Bonniaud
      European Respiratory Journal 59 (3) 2102711; DOI: 10.1183/13993003.02711-2021 Published 10 March 2022
    • Open Access
      Reply: Measurement of hypoxia in the lung in idiopathic pulmonary fibrosis: a matter of control
      Joanna C. Porter, Thida Win, Kjell Erlandsson, Kris Thielemans, Ashley M. Groves
      European Respiratory Journal 59 (3) 2103124; DOI: 10.1183/13993003.03124-2021 Published 10 March 2022
    • You have accessRestricted access
      Technical standards for respiratory oscillometry and bronchodilator response cut-offs
      Cindy Thamrin, Paul D. Robinson, Claude S. Farah, Gregory G. King on behalf of the authors of the ERS Technical Standards for Respiratory Oscillometry
      European Respiratory Journal 59 (3) 2102663; DOI: 10.1183/13993003.02663-2021 Published 3 March 2022
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European Respiratory Journal: 59 (3)
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