Abstract
Introduction: Different studies found a significant association between serial biomarkers in assessing severity and prognosis of patients with SARS-Cov-2. However role of admission biomarkers in prognostication remains uncertain.
Aim and objectives: The overall objective of our study to find any significant difference in admission biochemical parameters among survival and non-survival group.
Methods: 92 patients (age; 66+/-14, males- 53%) with confirmed or suspected patients included in the study. Comparison done between survivors (n-50, 54%) and non-survivor (n-42, 46%) groups.
Results: We compared biochemical parameters (Neutrophil Lymphocyte Ratio, CRP, Creatinine Kinase, Troponin T, D-Dimer, Pro NT-BNP, Procalcitonin, Lactate Dehydrogenase, Lactate and Ferritin).
Average age in survivor group (61 +/- 15) is less compared to non-survivor (70 +/- 12) ((p 0.002) groups.
Hypoxemia is more prevalent in non survivor group (7.8 +/- 2.2) than survivor group (9 +/- 3) on same inspired oxygen.
However, biochemical parameters only serum lactate (mmol; 1.5 v/s 2.1, P= 0.02) and serum ferritin (ug/L; 910 v/s 1602, P=0.04) predicted survival. In our opinion this two markers are very non specific and can be raised in many other conditions.
Conclusions: Serial biomarkers can help to monitor and predict outcome and prognosis of COVID 19 patients. However role of admission biomarkers for future prognostication remain doubtful. On the other hand our study reveals age, hypoxaemia on admission are the main prognostication factors and consideration for early escalation of care.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA910.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021