Abstract
Objective: Analyze differences in inflammatory parameters and evaluate their impact on the clinical course in COVID-19 and Non-COVID-19 community-acquired pneumonia (CAP).
Methods: Prospective observational study including all patients hospitalized for Non-COVID-19 CAP in 2020 and COVID-19 in march-may 2020. We measured serum inflammatory markers at hospital admission and clinical course. Poor outcome: in-hospital mortality and/or need for high-flow oxygen therapy and/or invasive mechanical ventilation.
Results: We analyzed 387 patients (308 COVID-19, 79 Non-COVID-19). Etiology was identified in 34.1% of Non- COVID-19 CAP. Figure 1: demographic characteristics, inflammatory markers and in-hospital course. Patients with COVID-19 had worse clinical course and major short-term mortality (11% vs 2.5%, p=0.002). Figure 2: inflammatory parameters in patients with poor outcome.
Conclusions: Non-COVID-19 CAP had higher CRP and D-dimer whereas LDH level and lymphopenia were higher in COVID-19 patients. Demographic characteristics and comorbidities of both groups were similar; however, COVID-19 pneumonias had worse outcome and higher in-hospital mortality.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA659.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021
