Abstract
Introduction: Pulmonary hypoplasia can cause decreased lung function and respiratory failure depending on its severity.
Aims: To evaluate clinical characteristics of patients with pulmonary hypoplasia.
Methods: Gender, age, complaints, age at diagnosis, diagnostic methods, parental consanguinity, presence of operation, age at operation and long-term complications of all patients with pulmonary hypoplasia were evaluated.
Results: Of 18 patients with pulmonary hypoplasia, 44% were female and median age was 10.5 (min:0.9; max:192) months. The complaints were respiratory distress and cough. Median age at diagnosis was 0.41 (min:0; max:36) months. Median duration of follow-up was 8 (min:0.5; max:184) months. Parental consanguinity was present in 33.3% of patients. 66.6% of patients were diagnosed by CT, 22.2% by chest radiography and 11.2% by prenatal ultrasonography. 7 had accompanying diaphragma hernia (DH) and 7 had congenital heart disease. Others had PCD, Jeune syndrome, MPS and Fraser syndrome. Median age at diagnosis of patients with DH was 0.03 (min:0; max:1) months, and earlier than others (p=0.007). Patients born with DH were hospitalized due to respiratory distress. Median age at operation of 9 patients was 2 (min:1; max:150) days. Most common cause of hospitalization in follow-up was pneumonia. There was correlation between age at diagnosis and number of pneumonia (r=0.654; p=0.026). 3 operated patients had chest deformity, 2 had scoliosis, and 2 had diaphragm eventration.
Conclusions: Pulmonary hypoplasia can be detected with respiratory distress symptoms in neonatal period, or it may occur incidentally in later life. Pulmonary infections can be reduced in patients who are diagnosed and treated early.
Footnotes
Cite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA580.
This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021