Late Breaking Abstract - RECEIVER trial: sustained use and improved outcomes with digitally supported COPD co-management

Abstract

Introduction: We co-designed a digital service (LenusCOPD) with patients to support value-based care and improve COPD outcomes. Service includes prompted daily patient-reported outcomes (PROs), self-management resources, structured clinical summary, Fitbit wearable and AirView home NIV data with asynchronous patient-clinician messaging.

Aims and objectives: We conducted an implementation-effectiveness observational cohort trial (RECEIVER, NCT04240353), including people with COPD with recent severe exacerbation or who require home CPAP or NIV. Recruitment commenced September 2019 and paused March 2020 at UK COVID-19 lockdown. Primary endpoint and other 12-month follow-up analyses on the data from the 83 recruited participants are in progress.

Methods: Web tracking analytics capture PRO completion. De-identified data including respiratory-related hospital admission events from LenusCOPD and comparator cohort is reviewed in NHS GG&C SafeHaven trusted research environment.

Results: Patients continue to use the app regularly across 12 months of follow-up, with >3.5 PRO sets completed/participant/week through study weeks 1-52. 58/83 participants completed PROs on >75% of follow-up study weeks. Greater reduction in annualised clinical events was noted in RECEIVER vs comparator cohorts at 12 months follow-up.

Conclusions: Sustained use of a co-designed COPD digital service is notable. Admission reduction in study participants exceeds the COVID-19 lockdown effect. Further secondary analyses including AI-based exacerbation detection from RECEIVER PRO and wearable data are in progress.